Investigating Variation in Hospital Acute Coronary Syndrome Outcomes
|ClinicalTrials.gov Identifier: NCT01819103|
Recruitment Status : Completed
First Posted : March 27, 2013
Last Update Posted : April 4, 2013
|Condition or disease|
|Acute Myocardial Infarction|
Over the last few years the chance of dying from a heart attack in England and Wales has reduced dramatically. Even so, there remain huge differences in mortality between hospitals. For example, up to a third of patients with a heart attack who attend hospitals in England are more likely to die than would be expected. That is, the type of treatment and the risk of death depend upon where a patient lives and which hospital they attend. In part, the variation in death may be due to the services available at the hospital or to factors such as socioeconomic deprivation. It may also relate to other factors such as depression, cardiac rehabilitation, patient experience of hospital care and whether patients take their medication after discharge from hospital.
Notably, the challenges posed by poor drug adherence to secondary prevention medications are recognised by the World Health Organisation as the highest area of priority for improving individual health throughout the world. In addition, Patient Reported Outcome Measures (PROMs) are set to be the cornerstone of the evaluation of patient experiences of National Health Service quality of care.
Using statistical approaches that include measures of quality of life, we propose to examine data about heart attacks in England and investigate the 'postcode lottery of care'. Our aim, using regional data about heart attacks is to identify and measure the effects of hospital care. This research will identify hospital qualities that promote improved patient care. In doing so, best practice will be highlighted and healthcare policy changed so that all patients will have an equal chance of surviving a heart attack.
|Study Type :||Observational [Patient Registry]|
|Actual Enrollment :||5555 participants|
|Target Follow-Up Duration:||12 Months|
|Official Title:||Evaluation of the Methods and Management of Acute Coronary Events-4: Investigating Variation in Hospital Acute Coronary Syndrome Outcomes|
|Study Start Date :||March 2011|
|Actual Primary Completion Date :||February 2013|
|Actual Study Completion Date :||March 2013|
Acute myocardial infarction
- Mortality [ Time Frame: 12 months ]
- Drug Adherence [ Time Frame: 12 month ]
- Health related quality of life assessement [ Time Frame: 12 month ]
Biospecimen Retention: Samples With DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01819103
|Principal Investigator:||Chris P Gale, PhD||University of Leeds|