DETECT and Retinal Outcomes in Hypertension
The purpose of this study is to study the impact of blood pressure on cognitive performance.
|Study Design:||Observational Model: Case Control
Time Perspective: Prospective
|Official Title:||The Effects of Blood Pressure on Cognitive Function: Examining the Use of Bedside Neuropsychological Testing During Acute Hypertensive Events|
- DETECT neurocognitive outcome scores (Z-scores) in association with blood pressure measures and retinal pathology (isolated retinal hemorrhage, grade III/IV hemorrhagic retinopathy) [ Time Frame: 12 months ] [ Designated as safety issue: No ]
We aim to determine the correlation (if any) between the severity of blood pressure and DETECT neurocognitive outcomes as well as the correlation (if any) between known Hypertensive retinal disease and DETECT neurocognitive outcomes. Appropriate statistical analysis will be performed to compare clinical retinal findings, BP values, and DETECT neurocognitive test outcomes.
Subject level data will only be collected on the day of Emergency Department presentation. Subjects will not be followed after their initial enrollment. The study duration is projected for 12 months
- Variance of DETECT scores (Z-score) attributed to reading level [ Time Frame: One year study periord (12 months) ] [ Designated as safety issue: No ]
|Study Start Date:||November 2012|
|Estimated Study Completion Date:||December 2016|
|Estimated Primary Completion Date:||December 2016 (Final data collection date for primary outcome measure)|
hypertension with medication controlled
hypertensive urgency no previous history or antihypertensives
asymptomatic normotensive control group
Four groups will be evaluated for possible impact of blood pressure on cognitive performance and retinal damage.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01815567
|Contact: Tamara Espinoza, MDfirstname.lastname@example.org|
|Contact: David W Wright, MDemail@example.com|
|United States, Georgia|
|Grady Memorial Hospital||Recruiting|
|Atlanta, Georgia, United States, 30303|
|Contact: Tamara Espinoza, MD firstname.lastname@example.org|
|Principal Investigator:||Tamara Espinoza, MD||Emory University|