Prehospital Cerebral Oxygenation During Cardiopulmonary Resuscitation (CPR)

This study is currently recruiting participants. (see Contacts and Locations)
Verified August 2015 by Hasselt University
Ziekenhuis Oost-Limburg
Information provided by (Responsible Party):
Cornelia Genbrugge, Hasselt University Identifier:
First received: March 6, 2013
Last updated: August 18, 2015
Last verified: August 2015
Near infrared spectroscopy (NIRS) is a technique that measures regional cerebral oxygenation in a non-invasive manner. Through the use of near infrared light, the difference between oxygenated and deoxygenated hemoglobin can be measured. By applying the Beer-Lamber law, a numeric result can be calculated. During a cardiac arrest, there is no stroke volume, no cardiac output and no cerebral perfusion. By using cerebral NIRS during out-of hospital cardiac arrest, low flow time and return of spontaneous circulation, this study wants to show the prognostic value of NIRS as extra monitoring.

Cardiac Arrest

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Cerebral Oxygenation During Resuscitation and Post-resuscitation Phase

Resource links provided by NLM:

Further study details as provided by Hasselt University:

Primary Outcome Measures:
  • prognostic value [ Time Frame: 1 year ] [ Designated as safety issue: No ]
    Prognostic value of cerebral oxygenation during CPR

Estimated Enrollment: 200
Study Start Date: May 2013
Estimated Study Completion Date: December 2015
Estimated Primary Completion Date: October 2015 (Final data collection date for primary outcome measure)

Ages Eligible for Study:   16 Years and older
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
pre-hospital cardiac arrest

Inclusion Criteria:

  • >16 year

Exclusion Criteria:

  • DNR code
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01806844

Contact: Cornelia Genbrugge, MD

Ziekenhuis Oost-Limburg Recruiting
Genk, Limburg, Belgium, 3600
Contact: Cornelia Genbrugge, MD   
Principal Investigator: Cornelia Genbrugge, MD         
Sub-Investigator: Cathy De Deyne, MD. PhD         
Sub-Investigator: Jo Dens, MD. PhD         
Universitair ziekenhuis Leuven Recruiting
Leuven, Vlaams Brabant, Belgium, 3000
Contact: Marc Sabbe, MD PhD   
Contact: Cornelia genbrugge         
GZA St Vincentius Recruiting
Antwerp, Belgium
Contact: Dr. Kumar, MD         
Sub-Investigator: Kumar, MD         
Ziekenhuis netwerk Antwerpen Recruiting
Antwerpen, Belgium, 2000
Contact: Cornelia Genbrugge, MD         
AZ Turnhout Recruiting
Turnhout, Belgium
Contact: Dr. Mertens, MD         
Sub-Investigator: Ilse Mertens         
Sponsors and Collaborators
Hasselt University
Ziekenhuis Oost-Limburg
Principal Investigator: Cornelia Genbrugge, MD Hasselt University
  More Information

Responsible Party: Cornelia Genbrugge, Dr. Genbrugge, Hasselt University Identifier: NCT01806844     History of Changes
Other Study ID Numbers: Copernicus I 
Study First Received: March 6, 2013
Last Updated: August 18, 2015
Health Authority: Belgium: Ethics Committee

Keywords provided by Hasselt University:
Cardiac arrest
Cerebral oxygenation

Additional relevant MeSH terms:
Heart Arrest
Cardiovascular Diseases
Heart Diseases processed this record on February 11, 2016