Vitamin D Levels In Patients Who Has Normal to Grade 2 Knee Arthroscopy Changes
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|ClinicalTrials.gov Identifier: NCT01764139|
Recruitment Status : Terminated (Lack of patients with recruitment criteria)
First Posted : January 9, 2013
Last Update Posted : March 17, 2016
Vitamin D deficiency has long been linked to musculoskeletal pain, and many other chronic disease conditions. Vitamin D is a nutrient that functions as a hormone precursor, and wide-ranging health effects are supported by the presence of vitamin D receptors in several cell types and tissues of the body (eg, lymphocytes and monocytes, brain, heart, pancreas, intestine, and placenta).In addition to its essential role of maintaining bone health, hypovitaminosis D has been implicated in the development of serious conditions, including diabetes, various types of cancer, and cardiovascular diseases.
Vitamin D is a unique prohormone that humans obtain in small amount from food, dietary supplements and largely by endogenous skin synthesis from 7-dehydrocholesterol with sunlight exposure. This endogenous synthesis produces the form vitamin D3 (cholecalciferol).Vitamin D deficiency and insufficiency are very common in the UK. Local audit at Chelmsford has shown severe deficiency of vitamin D among chronic pain patients.
The major source of vitamin D synthesis relies on sunlight exposure which is likely to be affected by modern lifestyles, which increasingly involve working indoors during daylight hours. This may be particularly important when combined with residence in northern latitudes and a cloudy climate.The proposed pilot study aims to identify percentage of vitamin D deficiency among knee pain patients by investigating eligible patients' blood for '25 hydroxy vitamin D'.
English speaking patients whose knee pain has not been resolved following knee arthroscopy are eligible for the study. Study will be carried out at the Broomfield hospital chronic pain department.
Duration will be around 6 months.
|Condition or disease||Intervention/treatment|
|Knee Pain||Procedure: Blood sampling|
|Study Type :||Observational|
|Actual Enrollment :||2 participants|
|Official Title:||Vitamin D Levels In Patients Who Has Normal to Grade 2 Knee Arthroscopy Changes or Who Did Not Improve Symptoms Following Minor Knee Arthroscopic Procedures|
|Study Start Date :||March 2013|
|Actual Primary Completion Date :||March 2014|
|Actual Study Completion Date :||March 2014|
Knee pain patients with minimal knee changes
Male & no pregnant female age between 18-40 yrs.
Procedure: Blood sampling
Other Name: Investigtion of Vitamin D levels
- The percentages of Vitamin D deficiency among the knee pain patients. [ Time Frame: 6months ]To identify the percentages of Vitamin D deficiency among the knee pain patients
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01764139
|Chelmsford, Essex, United Kingdom, CM1 7ET|