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The Effects of Low- and High-intensity Resistance Exercise on Force-velocity Characteristics in Older Adults

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ClinicalTrials.gov Identifier: NCT01707017
Recruitment Status : Completed
First Posted : October 15, 2012
Last Update Posted : February 20, 2013
Information provided by (Responsible Party):

Study Description
Brief Summary:
The purpose of this study is to compare the impact of high- and low-intensity resistance exercise on force-velocity characteristics, muscle mass and inflammatory processes in older adults. As all training protocols are designed to end with maximal effort, effects are expected to be similar between groups.

Condition or disease Intervention/treatment
Effects of Strength Training in Older Adults Other: Strength training

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 56 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Study Start Date : January 2012
Primary Completion Date : December 2012
Arms and Interventions

Arm Intervention/treatment
Active Comparator: High-load strength training Other: Strength training
Active Comparator: Low-load strength training Other: Strength training
Active Comparator: Low-load + moderate-load strength training Other: Strength training

Outcome Measures

Primary Outcome Measures :
  1. Change in force-velocity characteristics of knee extensors [ Time Frame: Baseline, 12weeks, 6 months ]

Other Outcome Measures:
  1. Change in muscle volume [ Time Frame: Baseline, 12weeks, 6 months ]
  2. Change in maximal strength (one repetition maximum) [ Time Frame: Baseline, 4weeks, 8weeks, 12weeks, 6 months ]
    Strength is measured as the maximum weight on the training equipment that can be lifted only one time (= one repetition maximum).

  3. Change in motivation [ Time Frame: Baseline, every week for 12 weeks, 6 months ]
  4. Change in physical activity [ Time Frame: Baseline, 12weeks, 6 months ]
  5. Change in inflammatory markers in blood [ Time Frame: Baseline, 12weeks, 6 months ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • age 60 to 80 years

Exclusion Criteria:

  • Knee or hip prothesis
  • Systematic training
  • Cardiovascular disease
  • Acute lower back pain
  • Dementia
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01707017

Faculty of Kinesiology and Rehabilitation Sciences
Leuven, Belgium, 3001
Sponsors and Collaborators
Universitaire Ziekenhuizen Leuven
More Information

Responsible Party: Universitaire Ziekenhuizen Leuven
ClinicalTrials.gov Identifier: NCT01707017     History of Changes
Other Study ID Numbers: S53709
First Posted: October 15, 2012    Key Record Dates
Last Update Posted: February 20, 2013
Last Verified: November 2011