CT-angiographic Follow up of Patients That Underwent Coronary Bypass Surgery Between 1993-1997
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|ClinicalTrials.gov Identifier: NCT01686100|
Recruitment Status : Completed
First Posted : September 17, 2012
Last Update Posted : September 19, 2012
Coronary artery surgery (CABG) is necessary to improve blood circulation in many patients with coronary artery disease. This is done by using alternative blood vessels (grafts) to bypass the stenosed coronary arteries. In CABG, vein grafts are traditionally used where surrounding tissue is removed, this may damage the vessel and influence its patency.
The "no-touch" technique was developed by Professor Domingos Souza at the Department of Cardiovascular and Thoracic Surgery, Örebro University Hospital. This technique includes taking out the vein with its surrounding tissue and by this way the vessel is less damaged. The first two follow ups have shown that no-touch grafts had better patency than conventionally extracted graft at 18 months and 8.5 years.
This long term follow up is a continuation of the randomized trial started in 1993 where the patency and incidence of stenoses in the no touch and conventional vein grafts has been studied.
|Condition or disease||Intervention/treatment||Phase|
|Coronary Artery Disease||Procedure: No touch technique Procedure: Conventional technique||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||52 participants|
|Intervention Model:||Parallel Assignment|
|Official Title:||CT-angiographic Follow Upp of Patients That Underwent Coronary Bypass Surgery Between 1993-1997. A Randomized Longitudinal Trial.|
|Study Start Date :||June 2010|
|Actual Primary Completion Date :||November 2011|
|Actual Study Completion Date :||November 2011|
Active Comparator: No touch vein grafts
The grafts were harvested with there surrounding tissues.
Procedure: No touch technique
The vein graft is harvested with its surronding tissues.
Active Comparator: Conventional vein grafts.
The grafts were stripped from surrounding tissue.
Procedure: Conventional technique
The vein graft is stripped from its surrounding tissues.
- Patency of the grafts [ Time Frame: Mean time of 15 years. ]
- Stenosis in the grafts. [ Time Frame: Mean time of 15 years. ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01686100
|Department for Cardiovascular and Thoracic Surgery, Örebro University Hospital|
|Örebro, Sweden, 70185|