Ventricular Volume as Assessed by Cardiac Magnetic Resonance
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|ClinicalTrials.gov Identifier: NCT01678040|
Recruitment Status : Unknown
Verified August 2012 by The Hospital for Sick Children.
Recruitment status was: Active, not recruiting
First Posted : September 3, 2012
Last Update Posted : September 3, 2012
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||15 participants|
|Official Title:||MRI Assessment of the Effect of Preload on Ventricular Volumes and Function in Healthy Adult Volunteers|
|Study Start Date :||May 2012|
|Actual Primary Completion Date :||August 2012|
|Estimated Study Completion Date :||December 2012|
Cardiac Magnetic Resonance
The CMR examinations will be performed in the cardiac MRI scanner (Siemens "Avanto", 1.5 Tesla, Erlangen, Germany) at the Hospital for Sick Children. A brief echocardiogram will be performed using a GE Vivid 7 or Vivid E9 machine (General Electric Medical Systems, Wisconsin, USA) We will image from standard parasternal long axis and apical four-chamber before and after completed hydration.
- Fluid Status [ Time Frame: Day 1 ]To assess ventricular volumes in the fasting state and after oral hydration in order to assess the effect of fluid status on ventricular volumes as measured by CMR.
- Hydration [ Time Frame: Day 1 ]To evaluate the effect of hydration on ventricular volumes compared the effect of with inter-observer and intra-observer variability.
- Chamber Deformation [ Time Frame: Day 1 ]To evaluate the effects of chamber volume on chamber deformation, including strain and peak strain rate
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01678040
|The Hospital for Sick Children|
|Toronto, Ontario, Canada, M5G 1X8|
|Principal Investigator:||Lars Grosse-Wortmann, MD||The Hospital for Sick Children|