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Screening Cardiovascular Patients for Aortic Aneurysms (SCAN)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01643317
Recruitment Status : Completed
First Posted : July 18, 2012
Last Update Posted : July 24, 2019
Information provided by (Responsible Party):
Joep Teijink, Catharina Ziekenhuis Eindhoven

Brief Summary:

Screening studies for Abdominal Aortic Aneurysms (AAA) in 65 to 79 years aged men, have shown a significant reduction in AAA related mortality. In addition, the cost-effectiveness of screening for AAA in men in the Netherlands has been demonstrated by using a Markov model. Screening might be even more (cost-) effective if targeted on high risk groups, such as patients with a particular cardiovascular disease with a known increased risk of having an AAA.

Project SCAN (Screening CardioVascular patients for Aortic aNeurysms) is a project focused on targeted AAA screening to proactively diagnose patients at high risk of having an aneurysm that eventually may rupture. This pilot project aims to study the value of a screening protocol in daily practice to detect AAA's in high risk patients.

Condition or disease
Abdominal Aortic Aneurysm

Detailed Description:
  1. Offering PAD and CAD patients a non-invasive abdominal ultrasound after a careful process of shared-decision making
  2. Recording data on aneurysm detection on all PAD and CAD patients screened:

    1. General information (age, gender)
    2. Medical history on CardioVascular risk factors (such as smoking history, hypertension, and other cardiovascular medical conditions - only information that is already recorded in the patient's medical history chart)
    3. AAA - Yes/ No (Yes if ≥3 cm AAA)
    4. If ≥3 cm aneurysm, record exact size and outcome in time (surveillance, treatment, no treatment)
    5. If treated, record treatment type (EVAR or Open) and outcome

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Study Type : Observational
Actual Enrollment : 35 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Screening Cardiovascular Patients for Aortic Aneurysms
Study Start Date : July 2012
Actual Primary Completion Date : July 2013
Actual Study Completion Date : July 2013

Resource links provided by the National Library of Medicine

Primary Outcome Measures :
  1. AAA prevalence [ Time Frame: 1 year ]

Information from the National Library of Medicine

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Ages Eligible for Study:   55 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with peripheral arterial disease or carotid arterial disease

Inclusion Criteria:

  • male and female patients
  • peripheral arterial disease (ankle brachial index < 0,90 and/or reduction of > 0.15 after exercise test) or a carotid stenosis (stenosis ≥ 50%)
  • age > 55 year

Exclusion Criteria:

  • Patients unfit for endovascular or open surgery (as judged by vascular surgeon)
  • Failure to master the dutch language

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01643317

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Catharina Hospital
Eindhoven, Netherlands
Sponsors and Collaborators
Catharina Ziekenhuis Eindhoven
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Responsible Party: Joep Teijink, MD, PhD, Vascular Surgeon, Catharina Ziekenhuis Eindhoven Identifier: NCT01643317    
Other Study ID Numbers: Catharina_Project_SCAN
First Posted: July 18, 2012    Key Record Dates
Last Update Posted: July 24, 2019
Last Verified: July 2019
Additional relevant MeSH terms:
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Aortic Aneurysm
Aortic Aneurysm, Abdominal
Vascular Diseases
Cardiovascular Diseases
Aortic Diseases