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The Effect of Attention Bias Modification Training on Reducing Depressive Symptoms
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified June 2012 by Wenhui Yang, Hunan Normal University.
Recruitment status was: Enrolling by invitation
Recruitment status was: Enrolling by invitation
Sponsor:
Hunan Normal University
Information provided by (Responsible Party):
Wenhui Yang, Hunan Normal University
ClinicalTrials.gov Identifier:
NCT01628016
First received: June 9, 2012
Last updated: June 25, 2012
Last verified: June 2012
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Purpose
The purpose of this study is to test whether attention bias modification training is an effective neurobehavioral therapy to improve depressive symptoms.That is whether attention bias modification training is superior to placebo in reducing depressive symptoms over 1 year after training.
| Condition | Intervention |
|---|---|
| Depressive Symptoms | Behavioral: a word dot-probe task for training procedure |
| Study Type: | Interventional |
| Study Design: | Allocation: Randomized Intervention Model: Parallel Assignment Masking: Double Blind (Participant, Investigator, Outcomes Assessor) Primary Purpose: Treatment |
| Official Title: | A Randomized, Double-blind, Placebo-Controlled Evaluation of the Efficacy of Attentional Bias Modification Training in the Treatment of Depressive Symptoms |
Further study details as provided by Wenhui Yang, Hunan Normal University:
Primary Outcome Measures:
- Change in Beck Depression Inventory-II [ Time Frame: Changes from the baseline in Beck Depression Inventory-II at pre-training to 0, 2 weeks, 4 weeks, 8 weeks, 3 months , 6 months, 12 months post-training ]The assessment points were pretraining(baseline), posttraining and follow-up at 2-week, 4-week,8-week,3-month, 6-month and 12-month after training completion.
Secondary Outcome Measures:
- Changes in attentional bias score at dot-probe task, State-Trait Anxiety Inventory-Trait(STAI-T) and Rumination Response Style（RRS） [ Time Frame: Changes from pre-training to post-training in attentional bias scores, and from the baseline in STAI-T and RRS at pre-training to 0, 2weeks, 4weeks, 8weeks, 3months , 6months and 12 months post-training ]
| Estimated Enrollment: | 99 |
| Study Start Date: | September 2011 |
| Estimated Study Completion Date: | October 2012 |
| Estimated Primary Completion Date: | October 2012 (Final data collection date for primary outcome measure) |
| Arms | Assigned Interventions |
|---|---|
|
Experimental: Attentional bias modification training
Participants complete 8 sessions of attention bias modification training (ABMT) during a two-week period. ABMT is a modified dot probe task, in which a probe always appears in the location of neutral stimulus after the two stimuli (i.e. one is the depressive cue and the other is neutral) were simultaneously presented. In the ABMT,the probability that a probe appears in the location of neutral is 90%, and correspondingly,in the location of depressive stimuli is 10%. Each session consists of 218 trials, and the time to complete a training session is approximately 10 minutes.
|
Behavioral: a word dot-probe task for training procedure
During a two-week period, 8 sessions of a modified dot probe task for attentional bias modification training (ABMT) condition, 8 sessions of a classic dot probe task for placebo training (PT) condition, only assessment for blank control condition.
|
|
Placebo Comparator: Placebo training
Participants complete 8 sessions of placebo training(PT) during a two-week period. Placebo training is a classic dot probe task, in which a probe appears after either of the locations that the two stimuli (i.e. one is the depressive cue and the other is neutral) were presented, with the same frequencies. In the PT condition, each session also consists of 218 trials, and the time to complete a PT session is approximately 10 minutes as well.
|
Behavioral: a word dot-probe task for training procedure
During a two-week period, 8 sessions of a modified dot probe task for attentional bias modification training (ABMT) condition, 8 sessions of a classic dot probe task for placebo training (PT) condition, only assessment for blank control condition.
|
|
No Intervention: blank control
Participants only complete assessment at each point time.
|
Behavioral: a word dot-probe task for training procedure
During a two-week period, 8 sessions of a modified dot probe task for attentional bias modification training (ABMT) condition, 8 sessions of a classic dot probe task for placebo training (PT) condition, only assessment for blank control condition.
|
Detailed Description:
Attentional bias has been theorized to play a critical role in the onset and maintenance of depression. Attentional bias modification training (ABMT), an experimental paradigm that uses training to induce adaptive attentional bias, was developed to test the causal model and this has therapeutic implications in depression.To test the effect of ABMT on treatment of depressive symptoms, a randomized, double-blind, placebo and blank controlled trial is conducted in college students who are experiencing mild-to-severe symptoms of depression.
Eligibility| Ages Eligible for Study: | 16 Years and older (Child, Adult, Senior) |
| Sexes Eligible for Study: | All |
| Accepts Healthy Volunteers: | No |
Criteria
Inclusion Criteria:
- A score of 14 or higher on the Beck Depression Inventory-II
Contacts and Locations
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Please refer to this study by its ClinicalTrials.gov identifier: NCT01628016
Please refer to this study by its ClinicalTrials.gov identifier: NCT01628016
Locations
| China, Hunan | |
| Department of Psychology, Hunan Normal University | |
| Changsha, Hunan, China, 400081 | |
Sponsors and Collaborators
Hunan Normal University
Investigators
| Principal Investigator: | Wenhui Yang, Ph.D | Department of Psychology, Hunan Normal University |
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
| Responsible Party: | Wenhui Yang, Department of Psychology, Hunan Normal University |
| ClinicalTrials.gov Identifier: | NCT01628016 History of Changes |
| Other Study ID Numbers: |
XJK011AXL002 |
| Study First Received: | June 9, 2012 |
| Last Updated: | June 25, 2012 |
Keywords provided by Wenhui Yang, Hunan Normal University:
|
depression attention training modification |
Additional relevant MeSH terms:
|
Depression Behavioral Symptoms |
ClinicalTrials.gov processed this record on July 17, 2017