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An Observational Retrospective Study to Evaluate Treatment Patterns of Botulinum Toxin Type A

This study has been completed.
Information provided by (Responsible Party):
Allergan Identifier:
First received: May 29, 2012
Last updated: June 25, 2012
Last verified: June 2012
This is a retrospective chart review to evaluate treatment patterns of botulinum toxin Type A for the treatment of facial lines.

Condition Intervention
Facial Rhytides
Drug: botulinum toxin Type A

Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Retrospective

Resource links provided by NLM:

Further study details as provided by Allergan:

Primary Outcome Measures:
  • Average Total Dose Per Treatment Period [ Time Frame: 24 Months ]
    Average total dose per treatment period was defined as total treatment dose plus total touch-up dose plus total follow-up dose.

Secondary Outcome Measures:
  • Inter-Injection Interval Duration of Each Treatment Period [ Time Frame: 24 Months ]
    Inter-injection interval duration of each treatment period. Duration is defined as the number of days of an injection cycle.

  • Percent of Subjects Reporting Satisfaction With Treatment Effects [ Time Frame: 24 Months ]
    Percent of subjects reporting satisfaction with treatment effects per chart notes.

Enrollment: 110
Study Start Date: April 2011
Study Completion Date: June 2011
Primary Completion Date: June 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
botulinum toxin Type A
Previous treatment with botulinum toxin Type A for treatment of facial lines
Drug: botulinum toxin Type A
Previous treatment with botulinum toxin Type A for treatment of facial lines
Other Names:
  • BOTOX®
  • Xeomin®


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Subjects treated for glabellar lines (hyperfunctional facial lines) with botulinum toxin Type A

Inclusion Criteria:

  • Previously treated for glabellar lines (hyperfunctional facial lines) with botulinum toxin Type A preparation
  • Received 2 treatment cycles wtih botulinum toxin Type A (BOTOX®) prior to at least 1 treatment with botulinum toxin Type A (Xeomin®)

Exclusion Criteria:

  Contacts and Locations
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Please refer to this study by its identifier: NCT01608659

Buenos Aires, Argentina
Sponsors and Collaborators
Study Director: Medical Director Allergan
  More Information

Responsible Party: Allergan Identifier: NCT01608659     History of Changes
Other Study ID Numbers: GMA-BTXC-10-001
Study First Received: May 29, 2012
Results First Received: June 25, 2012
Last Updated: June 25, 2012

Additional relevant MeSH terms:
Botulinum Toxins
Botulinum Toxins, Type A
Acetylcholine Release Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Cholinergic Agents
Neurotransmitter Agents
Physiological Effects of Drugs
Neuromuscular Agents
Peripheral Nervous System Agents processed this record on May 22, 2017