Non Invasive Measurement of Cardiac Index by Impedance Cardiography
Pulmonary hypertension (PH) is defined as a pulmonary arterial mean pressure (meanPAP) ≥ 25 mmHg in the right heart catheterization.
There are different forms of PH defined in the classification of Dana Point 2008.
PH is diagnosed with right heart catheterization but there are other non invasive methods which can be used for screening like echocardiography, stress echocardiography and cardio pulmonary exercise testing.
For prognosis of PH patients the limitation of the pulmonary circulation is very important. Therefore the cardiac index (CI) is a good parameter for the right ventricular function. The gold standard for CI measures is the thermodilution, an invasive method performed during right heart catheterization.
|Study Design:||Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Diagnostic
|Official Title:||Non Invasive Measurement of Cardiac Index by Impedance Cardiography|
- Comparison of CI measured by ICG and Thermodilution [ Time Frame: recruitment over 1.5 year (Data collection), followed by data analysis and interpretation (overall 2 yearsfrom start of recruitment) ] [ Designated as safety issue: No ]assessment of the Specificity and sensitivity of ICG for CI measurement
|Study Start Date:||March 2012|
|Estimated Study Completion Date:||July 2015|
|Estimated Primary Completion Date:||July 2015 (Final data collection date for primary outcome measure)|
Patients who undergo right heart catheterization for PH diagnosis undergo impedance cardiography
Other: Impedance cardiography
noninvasive measure of cardiac index by impedance cardiography.
Other Name: patients with a clinical suspicion of PH
In this study the investigators want to evaluate the impedance cardiography (ICG) as a non invasive method for CI measurement. An alternating current of max 400µA and 45 kHz is conducted through the body. The way of the smallest resistance is the blood in the aorta. The impedance changes with the pulsatile blood flow. Out of the Impedance change there can be calculated the CI.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01607515
|Contact: Horst Olschewski, MD||+43 316 385 email@example.com|
|Contact: Maria Tscherner, MD||+43 316 385 firstname.lastname@example.org|
|Medical University of Graz||Recruiting|
|Graz, Austria, 8036|
|Contact: Horst Olschewski, MD +43 316 385 12183 email@example.com|
|Contact: Maria Tscherner, MD +43 316 385 12183 firstname.lastname@example.org|
|Principal Investigator:||Horst Olschewski, MD||Medical University of Graz|