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Prevention and Reduction of Alcohol and Drug Problems in a Clinical Psychiatric Youth Population

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ClinicalTrials.gov Identifier: NCT01595568
Recruitment Status : Unknown
Verified July 2012 by Eveline Perrier-Ménard, St. Justine's Hospital.
Recruitment status was:  Recruiting
First Posted : May 10, 2012
Last Update Posted : July 19, 2012
Sponsor:
Information provided by (Responsible Party):
Eveline Perrier-Ménard, St. Justine's Hospital

Study Description
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Brief Summary:

In adolescents, mental health problems are frequently associated with substance misuse, even considered a risk factor for alcohol abuse and dependence. This dual diagnosis tends to complicate the patient's treatment and prognosis by increasing, among others, substance use problems, reckless behaviours, relationships and school problems and suicidal thoughts. It is therefore critical to invest time and effort into developing an efficient approach to prevent and reduce substance use problems and offer these children a more global and optimal treatment.

A brief personality-targeted intervention was developed with students of Canadian and English high schools based on four personality factors known to be implicated in the vulnerability to adolescent alcohol misuse (Impulsivity, Anxiety Sensitivity, Negative Thinking and Sensation Seeking) (Conrod et al., 2006,2008, O'Leary-Barrett 2010).

By helping the adolescents to develop better adaptive behaviours, this cognitive-behavioural intervention proved to reduce binge drinking, quantity and frequency of use and substance use problems (Conrod et al., 2006,2011).

The purpose of this study is to assess the impact of this intervention if combined to a regular treatment in a youth psychiatric population.

60 patients aged 14-17 years of a Child and Adolescent psychiatric department will be screened for personality risk with self-report assessments including the Substance Use Risk Profile Scale. Participants will be randomly assigned to a personality matched cognitive-behavioural intervention or a no-intervention control.

The main outcome measures of this study are alcohol and illicit drug outcomes. Secondary measures include mental health symptoms.


Condition or disease Intervention/treatment Phase
Alcohol Abuse Drug Abuse Mood Disorder Anxiety Disorder Conduct Disorder Behavioral: Personality-targeted interventions Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Study Start Date : February 2012
Estimated Primary Completion Date : July 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Anxiety

Arms and Interventions
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Arm Intervention/treatment
Experimental: Learning to cope with your impulsivity
Cognitive-behavioural intervention targeting impulsive personality
 Behavioral: Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
Other Names:
  • Preventure
  • Adventure
Experimental: Learning to cope with your sensation seeking
Cognitive behavioural intervention designed to help sensation seeking youth manage their need for stimulation and excitement.
 Behavioral: Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
Other Names:
  • Preventure
  • Adventure
Experimental: Learning to cope with your anxiety sensitivity
Cognitive behavioural intervention teaching anxiety sensitive youth to manager their sensitivity to threat and anxiety.
 Behavioral: Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
Other Names:
  • Preventure
  • Adventure
Experimental: Learning to manage your negative thinking
Cognitive behavioural intervention targeting pessimistic and negative thinking in hopeless youth
 Behavioral: Personality-targeted interventions
Motivational and cognitive behavioural interventions targeting four personality profiles. 2 90 minute group sessions with personality-matched peers facilitated by a trained therapist and co-facilitator
Other Names:
  • Preventure
  • Adventure


Outcome Measures
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Primary Outcome Measures :
  1. Change in Binge drinking frequency [ Time Frame: Baseline - 4months ]
  2. Change in Drinking frequency [ Time Frame: Baseline - 4 months ]
  3. Change in Drinking quantity [ Time Frame: Baseline - 4 months ]
  4. Change in Drinking problems [ Time Frame: Baseline - 4 months ]

Secondary Outcome Measures :
  1. Change in Emotional and behavioural problems [ Time Frame: Baseline - 4 months ]
    Psychiatric symptoms (depression, panic anxiety, antisocial behaviours), coping skills, motives for drinking, assessed using the Strengths and Difficulties Questionnaire, the Drinking Motives Questionnaire and the Brief Symptom Inventory.


Eligibility Criteria
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Information from the National Library of Medicine

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Ages Eligible for Study:   14 Years to 17 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Motive for psychiatric consultation
  • Able to provide consent from parent/guardian for participation in the study
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01595568


Contacts
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Contact: Eveline Perrier-Ménard, MD 514-345-4931 ext 4050 eveline.perrier-menard@umontreal.ca

Locations
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Canada, Quebec
CHU Ste-Justine Recruiting
Montréal, Quebec, Canada, H3T 1C5
Contact       eveline.perrier-menard@umontreal.ca   
Sponsors and Collaborators
St. Justine's Hospital
More Information
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Responsible Party: Eveline Perrier-Ménard, MD, Master student, St. Justine's Hospital
ClinicalTrials.gov Identifier: NCT01595568    
Other Study ID Numbers: CER CHU Ste-Justine 3435
First Posted: May 10, 2012    Key Record Dates
Last Update Posted: July 19, 2012
Last Verified: July 2012
Keywords provided by Eveline Perrier-Ménard, St. Justine's Hospital:
Adolescents
Dual Diagnosis
Mental Disorders
Substance Use Problems
Prevention
Additional relevant MeSH terms:
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Disease
Alcoholism
Substance-Related Disorders
Anxiety Disorders
Mood Disorders
Conduct Disorder
 Pathologic Processes
Mental Disorders
Alcohol-Related Disorders
Chemically-Induced Disorders
Attention Deficit and Disruptive Behavior Disorders
Neurodevelopmental Disorders