Accuracy of Oximeters With Hypoxia and Methemoglobin or Carboxyhemoglobin
|Healthy Volunteers||Device: Mespere Oximeter Device: Radiometer OSM-3 Co-Oximeter|
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Accuracy of Oximeters With Hypoxia and Methemoglobin or Carboxyhemoglobin|
- Venous Oxygen Saturation Accuracy Verification against Co-Oximeter [ Time Frame: approximately 1 hour ]
Biospecimen Retention: Samples With DNA
|Study Start Date:||September 2014|
|Study Completion Date:||October 2014|
|Primary Completion Date:||September 2014 (Final data collection date for primary outcome measure)|
9 subjects (male and female)
Device: Mespere Oximeter
Mespere oximeter provides non-invasive venous blood oxygen saturation.Device: Radiometer OSM-3 Co-Oximeter
OSM-3, a Radiometer manufactured hemoximeter, is intended for the photometric determination of hemoglobin.
The conventional pulse oximeter has been a standard in clinical care for non-invasive hemodynamic monitoring, which only measures the arterial blood oxygenation. There are many clinical situations where tissue hypoxia may exist despite normal values obtained by conventional pulse oximeter. This can be cause by inadequate monitoring of oxygen demand (i.e. venous oxygen saturation) of the tissues.
The existing method for venous blood oxygenation monitored is either through an invasive fiber optic catheter, or intermittently by blood sampling and CO-oximetry. However, catheterization can be costly and can include inherent risks. Therefore, due to the inherent risks of catheterization, venous oximetry is limited only to those critically ill patients. The clinical application of venous oximetry is numerous, including severe sepsis and septic shock, severe trauma and hemorrhagic shock, and heart failure and cardiac arrest.
More complete information on patient hemodynamics can be provided by non-invasively monitoring of venous blood oxygenation.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01583634
|United States, California|
|University of California, San Francisco, Induced Hypoxia Lab|
|San Francisco, California, United States, 94143|
|Principal Investigator:||Philip E Bickler, MD, PhD||University of California, San Francisco|