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Serum DCAMKL1 Pre and Post Treatment in Patients With Pancreatic Cancer

This study is ongoing, but not recruiting participants.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01580241
First Posted: April 18, 2012
Last Update Posted: August 22, 2017
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
University of Oklahoma
  Purpose
The investigators believe DCAMKL-1 is a stem cell tumor marker and is elevated in patients with pancreatic cancer. The investigators would like to analyze its expression pre and post treatment, to gauge the correlation between current pancreatic cancer therapies and the expression of DCAMKL-1

Condition
Pancreatic Cancer

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective
Official Title: Expression Patterns of Stem Cell Marker Doublecortin and CaM Kinase-Like-1 (DCAMKL-1) in Human Pancreatic Adenocarcinoma

Resource links provided by NLM:


Further study details as provided by University of Oklahoma:

Estimated Enrollment: 60
Study Start Date: October 2010
Estimated Study Completion Date: December 2018
Primary Completion Date: July 2015 (Final data collection date for primary outcome measure)
Groups/Cohorts
Surgery group
Patients with pancreatic cancer who undergo surgical treatment only
Chemotherapy group
Patients with pancreatic cancer who undergo chemotherapy treatment only
Neoadjuvant group
Patients with pancreatic cancer who undergo neoadjuvant chemotherapy and surgery
Adjuvant group
Patients with pancreatic cancer who undergo surgery followed by chemotherapy

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Human patients with pancreatic cancer undergo various treatments for pancreatic cancer. We will examine the expression of Dcamkl-1 pre and post therapy (including, chemotherapy only, surgery only, neoadjuvant and adjuvant therapies) to correlate treatment with a change in DCAMKl-1 expression.
Criteria

Inclusion Criteria:

  • pancreatic cancer

Exclusion Criteria:

  • age < 18, history of other types of cancer
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01580241


Locations
United States, Oklahoma
Stephensen Cancer Center
Oklahoma City, Oklahoma, United States, 73104
Sponsors and Collaborators
University of Oklahoma
Investigators
Principal Investigator: Courtney Houchen, MD University of Oklahoma
  More Information

Responsible Party: University of Oklahoma
ClinicalTrials.gov Identifier: NCT01580241     History of Changes
Other Study ID Numbers: 2606
First Submitted: April 17, 2012
First Posted: April 18, 2012
Last Update Posted: August 22, 2017
Last Verified: August 2017

Additional relevant MeSH terms:
Pancreatic Neoplasms
Digestive System Neoplasms
Neoplasms by Site
Neoplasms
Endocrine Gland Neoplasms
Digestive System Diseases
Pancreatic Diseases
Endocrine System Diseases