Try our beta test site
IMPORTANT: Listing of a study on this site does not reflect endorsement by the National Institutes of Health. Talk with a trusted healthcare professional before volunteering for a study. Read more...

LGG/BB12-pastille Study

This study has been completed.
University of Michigan
The Forsyth Institute
Information provided by (Responsible Party):
Eva Soderling, University of Turku Identifier:
First received: April 12, 2012
Last updated: January 3, 2013
Last verified: January 2013
We want to study the effect of short-term consumption of probiotics (a mixture of L. rhamnosus GG and B. lactis BB-12)on the composition of the oral flora.

Condition Intervention Phase
Dietary Supplement: Probiotics in an pastille
Dietary Supplement: Control pastille
Phase 1

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double Blind (Participant, Care Provider, Investigator, Outcomes Assessor)
Primary Purpose: Screening
Official Title: LGG/BB12-pastille Study

Further study details as provided by Eva Soderling, University of Turku:

Primary Outcome Measures:
  • Counts of mutans streptococci [ Time Frame: 4 weeks ]

Secondary Outcome Measures:
  • Amount of plaque [ Time Frame: 4 weeks ]

Enrollment: 60
Study Start Date: August 2012
Study Completion Date: November 2012
Primary Completion Date: November 2012 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
Experimental: Probiotic pastille
Test group
Dietary Supplement: Probiotics in an pastille
Test group
Active Comparator: Control pastille
Control group
Dietary Supplement: Control pastille
Control group


Ages Eligible for Study:   20 Years to 30 Years   (Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes

Inclusion Criteria:

  • Subjects healthy, 20-30 yrs of age

Exclusion Criteria:

  • Subjects not healthy, too old/young
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01577485

Institute of Dentistry
Turku, Finland, 20520
Sponsors and Collaborators
University of Turku
University of Michigan
The Forsyth Institute
Principal Investigator: Eva M Söderling Associate Professor
  More Information

Responsible Party: Eva Soderling, Associate Professor, University of Turku Identifier: NCT01577485     History of Changes
Other Study ID Numbers: ETMK:22/180/2012
Study First Received: April 12, 2012
Last Updated: January 3, 2013 processed this record on May 25, 2017