Akershus Cardiac Examination (ACE) 1950 Study (ACE1950)
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ClinicalTrials.gov Identifier: NCT01555411 |
Recruitment Status :
Recruiting
First Posted : March 15, 2012
Last Update Posted : April 14, 2021
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Condition or disease |
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Atrial Fibrillation Heart Failure Mild Cognitive Impairment Cardiovascular Diseases Cerebrovascular Disorders |
Design: The Akershus Cardiac Examination (ACE) 1950 Study is a population-based, prospective, cerebro- and cardiovascular age-cohort study of all men and women born in 1950 in Akershus County, Norway.
Time schedule: Study inclusion and baseline examinations took place in the period September 2012 - May 2015. Follow-up and sub-studies are ongoing.
Current status: As per May 2018, follow-up and sub-studies are ongoing.
Study Type : | Observational |
Estimated Enrollment : | 3706 participants |
Observational Model: | Cohort |
Time Perspective: | Prospective |
Official Title: | Akershus Cardiac Examination 1950 Study - a Cohort Study on Cardio- and Cerebrovascular Disease in 62-65-year-old Subjects |
Actual Study Start Date : | September 2012 |
Estimated Primary Completion Date : | December 1, 2050 |
Estimated Study Completion Date : | December 1, 2050 |

Group/Cohort |
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No treatment |
- Outcomes related to CVD and CV-associated conditions [ Time Frame: Maximum 35 years ]
- Specific CV endpoints; e.g. acute myocardial infarction, heart failure, atrial fibrillation, etc. [ Time Frame: Maximum 35 years ]
- Specific CV-associated conditions, including renal, cerebrovascular, pulmonary, etc. [ Time Frame: Maximum 35 years ]
- Specific clinical phenotypes; e.g. myocardial and arterial structure and function, lung function, etc. [ Time Frame: Maximum 35 years ]
- Impact of left atrial size and function measurements by echocardiography on stroke risk in an 62-65-year-old cohort [ Time Frame: Within 35 years ]
- Relation between cognitive function and sub-clinical CVD in a 62-65-year-old Norwegian population cohort [ Time Frame: Maximum 35 years ]
Biospecimen Retention: Samples With DNA

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Ages Eligible for Study: | 62 Years to 65 Years (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- Resident in Akershus County (as per October 2011, prior to study invitation)
- Born in the year of 1950
- Ability to consent to participation

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01555411
Contact: Arnljot Tveit, M.D., PhD | +47-67809924 | arnljot.tveit@vestreviken.no | |
Contact: Helge Røsjø, M.D., PhD | +47-91502900 | helge.rosjo@medisin.uio.no |
Norway | |
Akershus University Hospital | Recruiting |
Lørenskog, Akershus, Norway, 1478 | |
Contact: Helge Røsjø, MD, PhD +4791502900 helge.rosjo@medisin.uio.no | |
Contact: Magnus N Lyngbakken, MD Magnus.Nakrem.Lyngbakken@ahus.no | |
Sub-Investigator: Mohammad Osman Pervez, MD | |
Sub-Investigator: Thea Vigen, MD | |
Principal Investigator: Helge Røsjø, MD, PhD | |
Vestre Viken HT, Baerum Hospital, Department of Medical Research | Recruiting |
Sandvika, Akershus, Norway, 3004 | |
Contact: Arnljot Tveit, MD, PhD +4767809924 arnljot.tveit@vestreviken.no | |
Contact: Trygve Berge, MD +4767809117 trygve.berge@vestreviken.no | |
Sub-Investigator: Trygve Berge, MD | |
Sub-Investigator: Håkon Ihle-Hansen, MD | |
Principal Investigator: Arnljot Tveit, MD, PhD |
Study Director: | Arnljot Tveit, MD, PhD | Vestre Viken Hospital Trust, Department of Medical Research | |
Study Director: | Helge Røsjø, MD, PhD | University Hospital, Akershus | |
Principal Investigator: | Trygve Berge - member of steering committee, MD | Vestre Viken Hospital Trust, Department of Medical Research | |
Principal Investigator: | Pål Smith - member of steering committee, MD, PhD | University Hospital, Akershus | |
Principal Investigator: | Kjetil Steine - member of steering committee, MD, PhD | University Hospital, Akershus | |
Principal Investigator: | Torbjørn Omland - member of steering committee, MD, PhD | University Hospital, Akershus | |
Principal Investigator: | Magnus N Lyngbakken - member of steering committee, MD | University Hospital, Akershus |
Publications of Results:
Other Publications:
Responsible Party: | Vestre Viken Hospital Trust |
ClinicalTrials.gov Identifier: | NCT01555411 |
Other Study ID Numbers: |
2011/1475 C AFIA (initial study name) ( Other Identifier: Vestre Viken Hospital Trust and Akershus University Hospital ) |
First Posted: | March 15, 2012 Key Record Dates |
Last Update Posted: | April 14, 2021 |
Last Verified: | April 2021 |
Cardiovascular epidemiology Prospective, observational cohort study Biomarkers Cardio- and cerebrovascular imaging |
Cerebrovascular Disorders Atrial Fibrillation Cardiovascular Diseases Cognitive Dysfunction Heart Diseases Arrhythmias, Cardiac Pathologic Processes |
Cognition Disorders Neurocognitive Disorders Mental Disorders Brain Diseases Central Nervous System Diseases Nervous System Diseases Vascular Diseases |