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Plaqenil Role in Prevention of Age Related Macular Degeneration

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified January 2012 by Ziv Hospital.
Recruitment status was:  Recruiting
Sponsor:
ClinicalTrials.gov Identifier:
NCT01541449
First Posted: March 1, 2012
Last Update Posted: March 1, 2012
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Ziv Hospital
  Purpose
The investigators think that there is a connection between the use of plaquenil and the prevention of Age related macular degeneration (AMD). The investigators believe that the use of plaquenil makes bruch's membrane thicker, thereby preventing Chroidal Neovascularization (CNV) growth.

Condition
Age Related Macular Degeneration

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective
Official Title: Observational Study Between People That Use Plaquenil and Those Who do Not in Prevention of AMD.

Resource links provided by NLM:


Further study details as provided by Ziv Hospital:

Estimated Enrollment: 30
Study Start Date: January 2012
Estimated Study Completion Date: April 2012
Groups/Cohorts
RA patients treated with plaquenil
Patients who do not use plaquenil

Detailed Description:
the study is done by comparing to groups RA patients who take plaquenil Vs. group of patients who do not take plaquenil. after measuring the retina thickness we compare the avg. thickness of both groups.
  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
Ziv Medical center retina clinic population
Criteria

Inclusion Criteria:

  • all people who suffer from rheumatoid arthritis (RA) and use plaquenil

Exclusion Criteria:

  • patients who did not complete follow-up
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01541449


Contacts
Contact: Joseph Pikkel, M.D 0508434206 pikel.y@ziv.health.gov.il

Locations
Israel
Ziv Medical Center Recruiting
Safed, Israel, 13100
Contact: Otzem Chassid, M.D    0506266059    otzem@yahoo.com   
Sponsors and Collaborators
Ziv Hospital
Investigators
Principal Investigator: Joseph pikkel, M.D Ziv Medical Center
  More Information

Responsible Party: Ziv Hospital
ClinicalTrials.gov Identifier: NCT01541449     History of Changes
Other Study ID Numbers: ZIV-0061-11
First Submitted: February 2, 2012
First Posted: March 1, 2012
Last Update Posted: March 1, 2012
Last Verified: January 2012

Keywords provided by Ziv Hospital:
AMD
PLAQUENIL
CNV

Additional relevant MeSH terms:
Macular Degeneration
Retinal Degeneration
Retinal Diseases
Eye Diseases
Hydroxychloroquine
Antimalarials
Antiprotozoal Agents
Antiparasitic Agents
Anti-Infective Agents
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Antirheumatic Agents