Intelligence Changes Following Minor Surgery
Animal studies showed that many general anesthetics might result in neuron apoptosis and neurocognitive impairment in the developing brain. However results from human studies are conflicted. In present study, the investigators examined the association between early exposure to anesthesia and surgery for minor surgery and intelligence changes in adolescence using the Wechsler Intelligence Scale for Children.
|Study Design:||Observational Model: Cohort
Time Perspective: Prospective
|Official Title:||Intelligence Performance in Adolescence After Early Exposure to Anesthesia and Minor Surgery|
- Wechsler Intelligence Scale for Children [ Time Frame: Average 5 years after surgery ] [ Designated as safety issue: No ]Wechsler Intelligence Scale for Children will be done after surgery, the expected average of 5 years after surgery.
- Achenbach Child Behavior Checklist [ Time Frame: Average 5 years after surgery ] [ Designated as safety issue: No ]Wechsler Intelligence Scale for Children will be done after surgery, the expected average of 5 years after surgery.
|Study Start Date:||November 2011|
|Estimated Study Completion Date:||December 2012|
|Estimated Primary Completion Date:||October 2012 (Final data collection date for primary outcome measure)|
Please refer to this study by its ClinicalTrials.gov identifier: NCT01483313
|Shanghai, China, 200127|
|Principal Investigator:||Diansan Su, M.D., Ph.D||RenJi Hospital|