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Contingency Management for Persons With Severe Mental Illness

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ClinicalTrials.gov Identifier: NCT01478815
Recruitment Status : Completed
First Posted : November 23, 2011
Last Update Posted : January 16, 2013
Information provided by (Responsible Party):

Study Description
Brief Summary:
Contingency management is efficacious for treating cocaine abuse, but contingency management interventions have rarely been applied to patients with severe and persistent mental health problems. This pilot project will estimate effect sizes of contingency management for reducing cocaine use in patients receiving psychiatric care at a large community based mental health program. In total, 30 cocaine abusing patients will be randomized to one of two 8-week treatment conditions: standard care or standard care with contingency management. Patients in both conditions will provide breath and urine samples for toxicology testing twice per week. In the contingency management condition, patients will receive the opportunity to win prizes for submitting cocaine negative urine samples. The investigators expect that patients receiving contingency management will evidence reductions in cocaine use and may show improvements in psychiatric symptoms and psychosocial functioning relative to patients in standard care. Effect size estimates obtained from this study will be used to guide larger scale and longer duration evaluations of contingency management for dually diagnosed patients.

Condition or disease Intervention/treatment Phase
Substance Abuse Behavioral: contingency management Other: Standard Care Phase 2

Study Design

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 19 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: Contingency Management for Persons With Severe Mental Illness
Study Start Date : December 2011
Primary Completion Date : August 2012
Study Completion Date : August 2012

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Mental Disorders
U.S. FDA Resources

Arms and Interventions

Arm Intervention/treatment
Placebo Comparator: Standard Care Other: Standard Care
Standard Care
Experimental: Contingency management for abstinence from drugs Behavioral: contingency management
Participants will receive the opportunity to win prizes for submitting cocaine negative urine samples.

Outcome Measures

Primary Outcome Measures :
  1. longest continuous period of cocaine abstinence [ Time Frame: Week 8 ]

Secondary Outcome Measures :
  1. other drug use and psychosocial problems [ Time Frame: Week 8 ]

Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • age 18 years or older
  • meet DSM-IV criteria for cocaine abuse or dependence
  • English speaking
  • pass a brief quiz regarding study procedures to ensure understanding of the informed consent process.

Exclusion Criteria:

  • dementia
  • in recovery from pathological gambling
Contacts and Locations

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01478815

United States, Connecticut
Community Mental Health Affiliates, Inc.
New Britain, Connecticut, United States, 06051
Sponsors and Collaborators
UConn Health
National Institute on Drug Abuse (NIDA)
Principal Investigator: Nancy M Petry, Ph.D. UConn Health
More Information

Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: UConn Health
ClinicalTrials.gov Identifier: NCT01478815     History of Changes
Other Study ID Numbers: 12-070-3
P30DA023918 ( U.S. NIH Grant/Contract )
First Posted: November 23, 2011    Key Record Dates
Last Update Posted: January 16, 2013
Last Verified: December 2012

Additional relevant MeSH terms:
Substance-Related Disorders
Mental Disorders
Chemically-Induced Disorders