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CMR Repeatability in STEMI

This study has been completed.
Information provided by (Responsible Party):
Elisa McAlindon, University of Bristol Identifier:
First received: November 7, 2011
Last updated: October 27, 2014
Last verified: October 2014
The investigators propose to conduct a study to measure the reproducibility of CMR parameters that have been used to predict outcome following PPCI: infarct size, left ventricular volumes, myocardial salvage, microvascular obstruction (MVO) and myocardial oedema.


Study Type: Observational
Study Design: Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Cardiovascular Magnetic Resonance Scan Repeatability in ST Segment Elevation Myocardial Infarction

Further study details as provided by Elisa McAlindon, University of Bristol:

Primary Outcome Measures:
  • Inter-observer, intra-observer and inter-scan variability and agreement [ Time Frame: Between 2 scans ]

Enrollment: 40
Study Start Date: November 2011
Primary Completion Date: April 2013 (Final data collection date for primary outcome measure)


Ages Eligible for Study:   18 Years to 85 Years   (Adult, Senior)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
ST segment elevation myocardial infarction

Inclusion Criteria:

Participant may enter study if ALL of the following apply

  1. ST segment myocardial infarction as defined by ECG (by 2 contiguous limb leads with >1 mm ST-segment elevation, or >2 mm ST-segment elevation in contiguous precordial leads, or new LBBB) and > 20 minutes of cardiac chest pain
  2. Written informed consent

Exclusion Criteria:

Participant may not enter study if ANY of the following apply

  1. Contraindication to MRI (implanted pacemaker/ defibrillator, ferromagnetic metal implant/ injury, claustrophobia, obesity/ too large for CMR scanner)
  2. Known allergy to gadolinium
  3. Chronic atrial fibrillation
  4. Renal impairment with eGFR <30
  5. Cardiogenic shock
  6. Patients with special communication needs
  Contacts and Locations
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Please refer to this study by its identifier: NCT01468662

United Kingdom
Bristol Heart Institute
Bristol, United Kingdom, BS2 8HW
Sponsors and Collaborators
University of Bristol
Principal Investigator: Elisa McAlindon, BMBS University of Bristol
  More Information

Publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Elisa McAlindon, Cardiology Clinical Research Fellow, University of Bristol Identifier: NCT01468662     History of Changes
Other Study ID Numbers: Study 1569
Study First Received: November 7, 2011
Last Updated: October 27, 2014 processed this record on September 21, 2017