Cognitive Control Training for Depression
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|ClinicalTrials.gov Identifier: NCT01454141|
Recruitment Status : Completed
First Posted : October 18, 2011
Last Update Posted : October 18, 2011
|Condition or disease||Intervention/treatment|
|Depression||Other: Cognitive Control Training Other: Peripheral Vision Task|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||56 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Study Start Date :||July 2010|
|Primary Completion Date :||June 2011|
|Study Completion Date :||June 2011|
Experimental: Peripheral Vision Task
During this task participants viewed a circular array of 15 discs and were asked to move their attention, but not their eyes, clockwise around the array while auditory tones were presented. Following the presentation of a distinct target tone, the discs changed color and participants reported the color of the disc by pressing a designated button on the keyboard. This task was developed to be a non-active control condition, targeting visual and occipital areas of the brain, and therefore allows us to discriminate between the effects of completing a computer-based task from interventions that specifically target the PFC.
Other: Peripheral Vision Task
Three sessions of PVT.
Experimental: Cognitive Control Training
Cognitive Control Training (CCT) A modified version of the Paced Auditory Serial Addition Task (PASAT) and the Attention Control Intervention were used to train participants' attentional control in accordance with procedures used by Siegle and colleagues.
Other: Cognitive Control Training
Three sessions of CCT.
- Change in Beck Depression Inventory [ Time Frame: two weeks ]Change score in BDI was assessed between CCT and PVT groups.
- Change in Positive and Negative Affective Scale (PANAS) [ Time Frame: two weeks ]We looked at the change scores in positive and negative affectivity between CCT and PVT groups.
- Emotional Response and Recovery Task [ Time Frame: two weeks ]We looked at the emotional responses to IAPS images between CCT and PVT groups.
- Changes in Visual Analog Scales [ Time Frame: two weeks ]We looked at the change scores in visual analog scales (happy/sad) between CCT and PVT groups.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01454141
|United States, Massachusetts|
|Boston, Massachusetts, United States, 02215|