Causes, Analysis of the Sub-evaluating Coronary Syndromes Acute and Disparities in France in Women (CASSANDRE)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01394549
Recruitment Status : Completed
First Posted : July 14, 2011
Last Update Posted : June 21, 2012
Information provided by (Responsible Party):
Stephane MANZO-SILBERMAN, French Cardiology Society

Brief Summary:

Despite efforts of learned societies, community cardiology and more generally of most players in the health, cardiovascular diseases continue to be the leading cause of death among women in France and all over the Western world, there where they fell to second place among men. Clinical practice and the disparity between the sexes are still insufficiently known.

Multicenter observational study on a cross-week comparative basis with men

Condition or disease
Coronary Acute Syndrome

Detailed Description:

In France, as in other industrialized countries, ischemic heart disease is a major cause of morbidity and mortality in women. Work to improve epidemiological knowledge, prevention, screening, risk stratification and treatment of ischemic heart disease in women has a potential impact on all the issues listed.

There is therefore a double challenge:

  • A public health issue to alert the female population on cardiovascular risk and its consequences, while the female population does not feel concerned by the potential danger.
  • A challenge for health professionals so that they have the same thing vis-à-vis the cardiovascular prevention among women and whatever their field of practice.

Study Type : Observational
Actual Enrollment : 319 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Causes, Analysis of the Sub-evaluating Coronary Syndromes Acute and Disparities in France in Women
Study Start Date : June 2011
Actual Primary Completion Date : February 2012
Actual Study Completion Date : March 2012

The study includes all patients hospitalized for acute coronary syndrome during the week selected and who agreed to participate in the study.

Primary Outcome Measures :
  1. Clinical practices [ Time Frame: 1 day ]
    To assess clinical practices and disparities between men and women in the management of acute coronary syndrome

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
The study will be conducted in cardiac services regardless of the type of hospital where they are

Inclusion Criteria:

  • Women all patients and / or men regardless of age
  • Admitted to a cardiology department (in the intensive care unit or cardiology traditional) week of the survey,
  • Having presented an acute coronary syndrome, regardless of the type with or without ST segment above, with or without elevated troponin, complicated or not, regardless of its support invasive or conservative,
  • Patients who agreed to participate in the study.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01394549

CHU Amiens
Amiens, France
Sponsors and Collaborators
French Cardiology Society

WRITING GROUP MEMBERS, Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, De Simone G, Ferguson TB, Ford E, Furie K, Gillespie C, Go A, Greenlund K, Haase N, Hailpern S, Ho PM, Howard V, Kissela B, Kittner S, Lackland D, Lisabeth L, Marelli A, McDermott MM, Meigs J, Mozaffarian D, Mussolino M, Nichol G, Roger VL, Rosamond W, Sacco R, Sorlie P, Roger VL, Thom T, Wasserthiel-Smoller S, Wong ND, Wylie-Rosett J; American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics--2010 update: a report from the American Heart Association. Circulation. 2010 Feb 23;121(7):e46-e215. doi: 10.1161/CIRCULATIONAHA.109.192667. Epub 2009 Dec 17. Erratum in: Circulation. 2010 Mar 30;121(12):e260. Stafford, Randall [corrected to Roger, Véronique L]. Circulation. 2011 Oct 18;124(16):e425.

Responsible Party: Stephane MANZO-SILBERMAN, Assistant Professor, French Cardiology Society Identifier: NCT01394549     History of Changes
Other Study ID Numbers: 11320
First Posted: July 14, 2011    Key Record Dates
Last Update Posted: June 21, 2012
Last Verified: June 2012

Additional relevant MeSH terms:
Pathologic Processes