Intravenous (IV) Methylnaltrexone (MNTX) in the Prevention of Post-Operative Ileus
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A double-blind, randomized, parallel-group study designed to evaluate the safety and activity of IV MNTX in the treatment of Post-Operative Ileus (POI) in patients who underwent segmental colectomies via laparotomy.
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Ages Eligible for Study:
18 Years and older (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Males and females, 18 yrs or older
Patients who have undergone a segmental colectomy
Must be receiving opioids via IV.
Patients who received any experimental drug in the last 30 days
Patients receiving spinal medication for post-operative pain relief
Patients who have undergone operations for complications related to inflammatory bowel disease
Patients with recent history of abdominal radiation therapy.