Effect of Coconut Oil Application in Reducing Water Loss From Skin of Premature Babies in First Week of Life (TEWL) (TopOilTewl)
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|ClinicalTrials.gov Identifier: NCT01364948|
Recruitment Status : Completed
First Posted : June 3, 2011
Last Update Posted : June 3, 2011
|Condition or disease||Intervention/treatment||Phase|
|Trans Epidermal Water Loss (TEWL)||Other: Coconut oil application Other: No oil application||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||74 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||Effect of Topical Oil Application on Trans-epidermal Water Loss (TEWL) in Preterm Very Low Birth Weight (VLBW) Infants - A Randomized Clinical Trial|
|Study Start Date :||January 2006|
|Actual Primary Completion Date :||November 2006|
|Actual Study Completion Date :||December 2006|
Experimental: Coconut oil application
The oil (coconut oil) was applied by the trained nurse to the entire body surface of infant except the face two times a day starting at 12 hrs of life. Four ml of coconut oil was applied using both hands of the caregiver in four strokes. First stroke was from the clavicles over the chest and abdomen till the groin, second from the front of thighs over the knee and leg upto the sole, the third one from the shoulders over the arm and forearm till the palm continuing medially over the forearm and arm till the axilla and the final stroke was used for the back, starting from the upper back, continuing over the back of the thighs till the heel. Just prior to the first application, and thereafter prior to the subsequent applications the TEWL was recorded using the portable closed chamber evaporimeter. The oil application was continued twice daily (every 12 hrs at the same time as the hour of birth e.g. 11 am and 11pm) till the completion of the seventh day (168 hrs of life).
Other: Coconut oil application
Four ml coconut oil application twice daily for first week
No Intervention: No Oil Application
Babies in this group were not subjected to oil application. TEWL measurement was recorded every 12 hrs for the first week of life, at the same time as the hour of birth.
Other: No oil application
Oil application was not done
- Trans Epidermal Water Loss(TEWL) [ Time Frame: first 7 days of life ]TEWL was measured using evaporimeter(Vapometer, Delfin Technologies limited, Kuopio, Finland) at 12 hours of age and thereafter every 12 hours during the first week of life (168 hrs of life)
- Weight [ Time Frame: Weight first 7 days of life and 40 weeks postmenstrual age ]The weight of the neonate was recorded at birth and daily during the first week of life. The weight in grams and weight gain in grams/kilogram/day was measured at 40 weeks post conceptional age.
- Skin condition Score [ Time Frame: Skin condition Score at day 7 of life ]Skin Condition Score was measured using 'Lane and Drost' Score.This score has 9 scores from 1 to 9, 1 depicting the best skin state and 9 the worst with erythema, blistering & oozing over the entire area.
- Skin colonization pattern [ Time Frame: Skin colonization pattern at day 7 of life ]The skin swab cultures were sent after 1week of life to assess for skin colonization
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01364948
|All India Institute Of Medical Sciences|
|New Delhi, Delhi, India, 110029|
|Principal Investigator:||Dr Sushma Nangia, MBBS, MD||All India Institute of Medical Sciences, New Delhi|