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Analgesia After Cesarean Section

This study has been completed.
Information provided by:
Seoul National University Bundang Hospital Identifier:
First received: May 17, 2011
Last updated: May 24, 2011
Last verified: May 2011
Magnesium sulphate is the first line therapy for the management of preeclampsia and eclampsia in obstetrics. Perioperative administration of magnesium sulphate has been proved to be an effective as an analgesic adjuvant. The investigators evaluated the analgesic effect of magnesium in parturients undergoing Cesarean section.

Condition Intervention
Drug: Magnesium Sulphate

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Retrospective

Resource links provided by NLM:

Further study details as provided by Seoul National University Bundang Hospital:

Primary Outcome Measures:
  • Change of numeric rating scale (NRS) of postoperative pain during postoperative period [ Time Frame: postoperative 1, 2, 3, and 4 day ]

Secondary Outcome Measures:
  • incidence of stopping of intravenous PCA during postoperative 4 days [ Time Frame: during postoperative 4 days ]
  • serum magnesium level of group P [ Time Frame: preoperative 1 h and postoperative 1 day ]

Enrollment: 503
Study Start Date: December 2010
Study Completion Date: March 2011
Primary Completion Date: March 2011 (Final data collection date for primary outcome measure)
Groups/Cohorts Assigned Interventions
Group N
parturients who had undergone Cesarean section under the diagnosis of non-preeclampsia
Group P
parturients who had undergone Cesarean section under the diagnosis of preeclampsia
Drug: Magnesium Sulphate
Magnesium sulphate was infused for the management of preeclampsia at perioperative period.


Ages Eligible for Study:   20 Years to 50 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
medical record review

Inclusion Criteria:

  • parturients undergoing Cesarean section
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Please refer to this study by its identifier: NCT01360060

Korea, Republic of
Seoul national university bundang hospital
Seongnam, Gyeonggi, Korea, Republic of
Sponsors and Collaborators
Seoul National University Bundang Hospital
  More Information

Responsible Party: Hyoseok, Na/professor, Seoul National University Bundang Hospital Identifier: NCT01360060     History of Changes
Other Study ID Numbers: Mg_section
Study First Received: May 17, 2011
Last Updated: May 24, 2011

Additional relevant MeSH terms:
Hypertension, Pregnancy-Induced
Pregnancy Complications
Magnesium Sulfate
Sensory System Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Central Nervous System Depressants
Anti-Arrhythmia Agents
Calcium Channel Blockers
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Tocolytic Agents
Reproductive Control Agents processed this record on May 25, 2017