ClinicalTrials.gov
ClinicalTrials.gov Menu

Monitoring the Response of Port Wine Stain Birthmarks to Laser Therapy With Wide-field Functional Imaging Technologies

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT01333553
Recruitment Status : Completed
First Posted : April 12, 2011
Last Update Posted : May 1, 2018
Sponsor:
Collaborator:
Beckman Laser Institute University of California Irvine
Information provided by (Responsible Party):
Beckman Laser Institute and Medical Center, University of California, Irvine

Brief Summary:
The researcher develop non-invasive imaging modalities for assessment of port wine stain during laser therapy treatment of Port Wine Stain. The imaging modalities will be used to guide immediate retreatment of regions of persistent perfusion during the procedure.

Condition or disease Intervention/treatment
PORT WINE STAIN Device: Image-guided remove Port Wine Stain

Detailed Description:
The researcher can use imaging system operates by projecting low-power near-infrared structured light patterns on to the tissue of interest in a non-contact, reflection geometry and then capturing the reflectance with a camera.The system can image the depth-resolved optical properties of in-vivo tissues, allowing rapid, non-invasive visualization of sub-surface structures of Port Wine Stain.

Study Type : Observational
Actual Enrollment : 69 participants
Observational Model: Case-Only
Time Perspective: Prospective
Official Title: Monitoring the Response of Port Wine Stain Birthmarks to Laser Therapy With Wide-field
Study Start Date : April 2010
Actual Primary Completion Date : April 2018
Actual Study Completion Date : April 2018


Group/Cohort Intervention/treatment
Image-guided remove Port Wine Stain
Image-guided surgery remove Port Wine Stain
Device: Image-guided remove Port Wine Stain
Image-guided surgery remove Port Wine Stain




Primary Outcome Measures :
  1. Image-guided surgery remove Port Wine Stain [ Time Frame: 24 hours ]
    Image-guided surgery remove Port Wine Stain



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Study population will be selected from an outpatient population with Port Wine Stain birthmark at Beckman Laser Institute and Medical Clinic, University of California, Irvine. Patients with Port Wine Stain birthmark will be candidates for participation.
Criteria

Inclusion Criteria:

  • All minors, birth to 18 years of age or older with Port Wine Stain birthmark
  • Ability to understand and carry out subject instructions
  • Sign photograph release form

Exclusion Criteria:

  • Inability to understand and/or carry out instructions
  • Pregnant women
  • Do not sign photograph release form

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01333553


Locations
United States, California
Beckman Laser Institute Medical clinic
Irvine, California, United States, 92612
Sponsors and Collaborators
University of California, Irvine
Beckman Laser Institute University of California Irvine
Investigators
Principal Investigator: Bernard Choi, PhD Beckman Laser Institute University of California Irvine

Responsible Party: Beckman Laser Institute and Medical Center, Bernard Choi, Ph.D., Assistant Professor Biomedical Engineering, University of California, Irvine
ClinicalTrials.gov Identifier: NCT01333553     History of Changes
Other Study ID Numbers: NIH/LAMMP-2010-7376
First Posted: April 12, 2011    Key Record Dates
Last Update Posted: May 1, 2018
Last Verified: April 2018

Keywords provided by Beckman Laser Institute and Medical Center, University of California, Irvine:
birthmark

Additional relevant MeSH terms:
Port-Wine Stain
Hemangioma, Capillary
Vascular Malformations
Skin Abnormalities
Congenital Abnormalities
Skin Diseases
Hemangioma
Neoplasms, Vascular Tissue
Neoplasms by Histologic Type
Neoplasms
Cardiovascular Abnormalities
Cardiovascular Diseases