We are updating the design of this site. Learn more.
Show more
ClinicalTrials.gov
ClinicalTrials.gov Menu

Pulsed Dye Laser for the Psoriatic Nail

This study has been completed.
Sponsor:
ClinicalTrials.gov Identifier:
NCT01303185
First Posted: February 24, 2011
Last Update Posted: December 12, 2014
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
Information provided by (Responsible Party):
Ying-Yi Chiang, Taipei Medical University WanFang Hospital
  Purpose
The treatment options for nail psoriasis have been limited, and the management of nail psoriasis has been challenging for physicians.To evaluate the effect of pulsed dye laser (PDL) in the treatment of nail psoriasis.

Condition
Psoriatic Nail

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Pulsed Dye Laser for the Psoriatic Nail

Further study details as provided by Ying-Yi Chiang, Taipei Medical University WanFang Hospital:

Primary Outcome Measures:
  • NAPSI [ Time Frame: 3rd and 6th months ]
  • global physician assessment [ Time Frame: 3rd and 6th months ]

Enrollment: 25
Study Start Date: January 2011
Study Completion Date: February 2012
Primary Completion Date: February 2012 (Final data collection date for primary outcome measure)
Groups/Cohorts
Experimental Group
Control Group

Detailed Description:
Psoriatic nails of patient's right hand were treated using PDL (595 nm) .The pulsed duration is 1.5ms, the beam diameter is 7mm, and the laser energy is 8.0 to 10.0 J/cm2. The treatment course of pulse dye laser is once monthly for 6 months. Psoriatic nails of both hands are treated with Tazarotene cream for 6 months. Clinical efficacy is statistically evaluated according to Nail Psoriasis Severity Index (NAPSI) score differences between right and left hand one month after 3rd and 6th therapy.
  Eligibility

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   16 Years and older   (Child, Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Psoriatic nail patients
Criteria

Inclusion Criteria:

  • Psoriatic nail refractory to other topical and systemic treatment therapy
  • ≧ 16 years old

Exclusion Criteria:

  • Patient with pregnancy
  • Patient with photo sensitivity
  • Patient with severe wound around finger nails or paronychia
  • Patient with hypersensitivity to Tazarotene cream
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01303185


Locations
Taiwan
Taipei Medical University - WanFang Hospital
Taipei, Taiwan
Sponsors and Collaborators
Taipei Medical University WanFang Hospital
Investigators
Principal Investigator: Ying-Yi Chiang Taipei Medical University WanFang Hospital
  More Information

Responsible Party: Ying-Yi Chiang, Attending Physician, Taipei Medical University WanFang Hospital
ClinicalTrials.gov Identifier: NCT01303185     History of Changes
Other Study ID Numbers: 99074
First Submitted: February 22, 2011
First Posted: February 24, 2011
Last Update Posted: December 12, 2014
Last Verified: December 2014

Keywords provided by Ying-Yi Chiang, Taipei Medical University WanFang Hospital:
Psoriatic Nail
Pulsed dye laser