Pulsed Dye Laser for the Psoriatic Nail
This study has been completed.
Information provided by (Responsible Party):
Ying-Yi Chiang, Taipei Medical University WanFang Hospital
First received: February 22, 2011
Last updated: December 11, 2014
Last verified: December 2014
The treatment options for nail psoriasis have been limited, and the management of nail psoriasis has been challenging for physicians.To evaluate the effect of pulsed dye laser (PDL) in the treatment of nail psoriasis.
||Observational Model: Case Control
Time Perspective: Prospective
||Pulsed Dye Laser for the Psoriatic Nail
Primary Outcome Measures:
- NAPSI [ Time Frame: 3rd and 6th months ] [ Designated as safety issue: No ]
- global physician assessment [ Time Frame: 3rd and 6th months ] [ Designated as safety issue: No ]
| Study Start Date:
| Study Completion Date:
| Primary Completion Date:
||February 2012 (Final data collection date for primary outcome measure)
Psoriatic nails of patient's right hand were treated using PDL (595 nm) .The pulsed duration is 1.5ms, the beam diameter is 7mm, and the laser energy is 8.0 to 10.0 J/cm2. The treatment course of pulse dye laser is once monthly for 6 months. Psoriatic nails of both hands are treated with Tazarotene cream for 6 months. Clinical efficacy is statistically evaluated according to Nail Psoriasis Severity Index (NAPSI) score differences between right and left hand one month after 3rd and 6th therapy.
|Ages Eligible for Study:
||16 Years and older
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
- Psoriatic nail refractory to other topical and systemic treatment therapy
- ≧ 16 years old
- Patient with pregnancy
- Patient with photo sensitivity
- Patient with severe wound around finger nails or paronychia
- Patient with hypersensitivity to Tazarotene cream
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study.
To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below.
For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01303185
|Taipei Medical University - WanFang Hospital
|Taipei, Taiwan |
Taipei Medical University WanFang Hospital
||Taipei Medical University WanFang Hospital
No publications provided
||Ying-Yi Chiang, Attending Physician, Taipei Medical University WanFang Hospital
History of Changes
|Other Study ID Numbers:
|Study First Received:
||February 22, 2011
||December 11, 2014
||Taiwan: Department of Health
Keywords provided by Taipei Medical University WanFang Hospital:
ClinicalTrials.gov processed this record on February 27, 2015
Pulsed dye laser