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Genetic Assessment of the Patients With Metabolic Syndrome (GENMetS)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified December 2010 by Medical Universtity of Lodz.
Recruitment status was:  Active, not recruiting
Information provided by:
Medical Universtity of Lodz Identifier:
First received: December 28, 2010
Last updated: July 20, 2011
Last verified: December 2010

Metabolic syndrome is a combination of medical disorders that increase the risk of developing cardiovascular disease and diabetes. The exact mechanisms of the complex pathways of metabolic syndrome are not yet completely known. The pathophysiology is extremely complex and has been only partially elucidated. Most patients are older, obese, sedentary, and have a degree of insulin resistance. Stress can also be a contributing factor. The most important factors are:

weight, genetics, aging, sedentary lifestyle,excess caloric intake. In our study we will assess the role of some polymorphisms in the pathology of metabolic syndrome.

Metabolic Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Prospective
Official Title: Genetic Assessment of the Patients With Metabolic Syndrome in Polish Population

Resource links provided by NLM:

Further study details as provided by Medical Universtity of Lodz:

Biospecimen Retention:   Samples With DNA
the blood samples taken into EDTA

Estimated Enrollment: 300
Study Start Date: December 2010
Estimated Study Completion Date: January 2015
Estimated Primary Completion Date: August 2011 (Final data collection date for primary outcome measure)
control group
healthy volunteers
Metabolic group
Patients with metabolic syndrome

Detailed Description:

Eligibility criteria to the study:

  • patients with metabolic syndrome
  • with written consent

Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Patients with metabolic syndrome

Inclusion Criteria:

  • patients with metabolic syndrome according to IDF,AHA and NHLBI 2009

Exclusion Criteria:

  • diabetes type 1
  • cancer
  • not consent
  • steroid therapy
  • alcohol or drug abuse
  • chronic inflammatory disease
  • pregnancy or lactation
  • severe hypothyroidism
  • immunosuppressive treatment
  • operation or severe injury during the last month
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01268696

Department of medical biotechnology Medical University of Lodz
Lodz, Poland
Sponsors and Collaborators
Medical Universtity of Lodz
Study Chair: Tadeusz Pietrucha, prof. Department of medical biotechnology
  More Information

Responsible Party: Department of Medical Biotechnology, Medical University of Lodz Identifier: NCT01268696     History of Changes
Other Study ID Numbers: RNN/202/10/KE
Study First Received: December 28, 2010
Last Updated: July 20, 2011

Keywords provided by Medical Universtity of Lodz:

Additional relevant MeSH terms:
Metabolic Syndrome X
Pathologic Processes
Insulin Resistance
Glucose Metabolism Disorders
Metabolic Diseases processed this record on September 19, 2017