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Impact of Morning Symptoms in Clinical Control of Chronic Obstructive Pulmonary Disease (COPD) (IMPAEPOC)

This study has been completed.
Information provided by:
AstraZeneca Identifier:
First received: December 21, 2010
Last updated: August 8, 2011
Last verified: August 2011
Observational study to know the Impact of morning symptoms in clinical control of COPD patients. 1200 patients will be included by General practitioners (GPs) and pneumologists. Objective: establish if there are differences in the impact of COPD on daily activities and morning symptoms measured through questionnaires of daily life activity (Capacity of Daily Living during the Morning (CDLM), Global Chest Symptoms Questionnaire (GCSQ))


Study Type: Observational
Study Design: Time Perspective: Cross-Sectional
Official Title: Impact of Morning Symptoms in Clinical Control of COPD

Further study details as provided by AstraZeneca:

Primary Outcome Measures:
  • Determine if there are differences in the impact of COPD on patients according to the characteristics of the disease. To measure the impact of specific self-administered questionnaires used in COPD: CDLMQ, GCSQ and CCQ [ Time Frame: Retrospective, (previous 24 months) ]
    Capacity of Daily Living during the Morning Qustionnaire (CDLMQ), Global Chest Symptoms Questionnaire (GCSQ)and COPD Control Questionnaire (CCQ)

Secondary Outcome Measures:
  • Assess comorbidities as a risk factor for frequent exacerbations [ Time Frame: Retrospective, (previous 24 months) ]

Enrollment: 1268
Study Start Date: January 2010
Study Completion Date: July 2011

Ages Eligible for Study:   40 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
General Practitioners and pneumologist

Inclusion Criteria:

  • Patient has signed informed consent form
  • Patients of both sexes,> 40 years.
  • Patients diagnosed with COPD according to global consensus on the definition, classification and management of the disease (GOLD) criteria:

    • post-bronchodilator forced expiratory volume in 1 s (FEV1) / forced vital capacity (FVC) <70%
    • post-bronchodilator FEV1 <80% (stage II, III and IV)

Exclusion Criteria:

  • Participating in an epidemiological study or clinical trial
  • Patient with other respiratory disease than COPD (eg bronchial asthma, cystic fibrosis, severe bronchiectasis, restrictive lung disease, cancer, etc.).
  • Patients with mild COPD: FEV1> 80%
  Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its identifier: NCT01266395

  Show 52 Study Locations
Sponsors and Collaborators
  More Information

Responsible Party: MC MD, AstraZeneca Identifier: NCT01266395     History of Changes
Other Study ID Numbers: NIS-RES-DUM-2010/2
Study First Received: December 21, 2010
Last Updated: August 8, 2011

Keywords provided by AstraZeneca:
morning symptoms COPD

Additional relevant MeSH terms:
Pulmonary Disease, Chronic Obstructive
Lung Diseases, Obstructive
Lung Diseases
Respiratory Tract Diseases processed this record on September 21, 2017