Risk Factor and Outcome of Candidemia

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01249313
Recruitment Status : Unknown
Verified June 2011 by China Medical University Hospital.
Recruitment status was:  Not yet recruiting
First Posted : November 29, 2010
Last Update Posted : June 27, 2011
Information provided by:
China Medical University Hospital

Brief Summary:

Candidemia is the fourth leading cause of hospital-acquired infection in USA. In CMUH, it caused 9% hospital-acquired bloodstream infection in 2008 and 2009. In addition to increased mortality, candidemia also increased hospital stay and cost. There is a trend of increased cases of candidemia in recent years in CMUH. Early empirical and target treatment can reduce mortality and shortened length of hospital stay.

In the past, most prior studies in Taiwan dealt with risk factors for mortality rather than for candidemia and also focused at in vitro susceptibility to antifungal agents. In this study, the investigators hope to analyze the candidemic cases from 2003 to 2009, estimated 1000 cases. There were some rare Candida species. Therefore, the investigators hope to do case study for these diseases to provide the epidemiology of candidemia in CMUH. The result can help clinician in predicting the disease and its outcome. Besides, it also provides the epidemiology of candidemia in mid-Taiwan.

Condition or disease

Study Type : Observational
Estimated Enrollment : 1000 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Study Start Date : September 2011
Estimated Primary Completion Date : April 2012
Estimated Study Completion Date : December 2012

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Ages Eligible for Study:   18 Years to 90 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
patient had candidemia from 2002-2010

Inclusion Criteria:

  • patient had candidemia from 2002-2010

Exclusion Criteria:

Responsible Party: Chia Hui Chou, Division of Infectious Disease, China Medical University Identifier: NCT01249313     History of Changes
Other Study ID Numbers: DMR99-IRB-237
First Posted: November 29, 2010    Key Record Dates
Last Update Posted: June 27, 2011
Last Verified: June 2011

Keywords provided by China Medical University Hospital:

Additional relevant MeSH terms:
Candidiasis, Invasive
Invasive Fungal Infections
Systemic Inflammatory Response Syndrome
Pathologic Processes