Effects of Cash Transfer for the Prevention of HIV in Young South African Women
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ClinicalTrials.gov Identifier: NCT01233531 |
Recruitment Status
:
Completed
First Posted
: November 3, 2010
Last Update Posted
: January 21, 2016
|
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
HIV | Behavioral: monthly cash transfer payments for attending school Behavioral: B--No cash transfers | Phase 3 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 2537 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Prevention |
Official Title: | Effects of Cash Transfer for the Prevention of HIV in Young South African Women |
Study Start Date : | March 2011 |
Actual Primary Completion Date : | March 2015 |
Actual Study Completion Date : | March 2015 |

Arm | Intervention/treatment |
---|---|
A--Monthly cash transfers
Monthly cash transfer payments
|
Behavioral: monthly cash transfer payments for attending school
In the intervention, young women and their households will be randomized in 1:1 ratio to receive monthly cash transfer payments, conditional on the young woman attending school, or to the control arm. Young women will be recruited at the beginning of grades 8 through 11 in the first year of the study.
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B--No cash transfers
No cash transfers.
|
Behavioral: monthly cash transfer payments for attending school
In the intervention, young women and their households will be randomized in 1:1 ratio to receive monthly cash transfer payments, conditional on the young woman attending school, or to the control arm. Young women will be recruited at the beginning of grades 8 through 11 in the first year of the study.
Behavioral: B--No cash transfers
No monthly cash transfers
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- HIV Incidence [ Time Frame: 4 years ]To determine whether young women who are randomized to receive CCTs conditional on school attendance have a lower incidence of HIV infection over time compared to young women who are not randomized to receive cash transfers.
- HSV-2 incidence [ Time Frame: 4 years ]To determine whether young women who are randomized to receive CCTs conditional on school attendance have a lower incidence of Herpes Simplex Virus type 2 (HSV-2) infections over time compared to young women who are not randomized to receive cash transfers.
- HSV Incidence [ Time Frame: 4 years ]To determine whether young women who receive the CCTs report less unprotected sex, fewer number of sexual partners, younger male partners, an older age of coital debut, a lower incidence of self-reported pregnancy, and greater school attendance compared to young women who do not receive the cash transfers.

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Ages Eligible for Study: | 13 Years to 20 Years (Child, Adult) |
Sexes Eligible for Study: | Female |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
- Female aged 13 to 20 years.
- Enrolled in grades 8, 9, 10 or 11 at the beginning of the study at schools in the AHDSS study site
- Intending to continue to live in the study site until the end of the follow-up period.
- Be willing and able to consent/assent to all study procedures including HIV and HSV-2 testing.
- Able to read sufficiently to use ACASI.
- Have a bank or post office account or have documentation to be able to open a bank or post office account (i.e., birth certificate, South African National Identification Book, or passport and proof of residence). Post Office accounts will only be required for participants in the Intervention arm.
- Parent/Legal Guardian who lives with young woman, willing and able to consent to all study procedures including HIV and HSV-2 testing.
- Parent/Legal Guardian has a bank or post office account or has documentation to be able to open a bank or post office account (i.e. South African National Identification Book, or passport and proof of residence). Note that the account may be opened in the name of any adult who resides in the household with the young woman.
Exclusion Criteria:
- Pregnant by self-report at baseline.
- Married at baseline.
- No parent or legal guardian living in household.
- Any other reason that the staff feels would jeopardize the health or well-being of the participant or staff or would prevent proper conduct of the study.

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01233531
South Africa | |
Agincourt | |
Acornhoek, South Africa |
Study Chair: | Audrey Pettifor | University of North Carolina | |
Principal Investigator: | Xavier Gomez-Olive | Wits Rural Public Health and Health Transitions Research Unit | |
Principal Investigator: | Kathleen Kahn | University of Witwatersrand, South Africa | |
Principal Investigator: | Catherine McPhail | Reproductive Health & HIV Research Unit, University of Witwatersrand |
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | HIV Prevention Trials Network |
ClinicalTrials.gov Identifier: | NCT01233531 History of Changes |
Other Study ID Numbers: |
HPTN 068 11710 ( Other Identifier: DAIDS ID: 11710 ) UM1AI068619 ( U.S. NIH Grant/Contract ) |
First Posted: | November 3, 2010 Key Record Dates |
Last Update Posted: | January 21, 2016 |
Last Verified: | January 2016 |