Effects of Exercise for Overweight Women With Polycystic Ovary Syndrome (POLY)
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|ClinicalTrials.gov Identifier: NCT01150539|
Recruitment Status : Completed
First Posted : June 25, 2010
Last Update Posted : May 24, 2018
|Condition or disease||Intervention/treatment||Phase|
|Polycystic Ovary Syndrome Obesity||Other: 16-week exercise training program Other: Control Group without PCOS||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||8 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Effects of Physical Activity on Insulin Resistance and Adiposity in Polycystic Ovary Syndrome "Poly"|
|Study Start Date :||January 2007|
|Actual Primary Completion Date :||May 2007|
|Actual Study Completion Date :||June 2007|
Experimental: Overweight/obese women with PCOS
10 overweight/obese women with polycystic ovary syndrome
Other: 16-week exercise training program
The primary objective of the study is to investigate the effects of a 16-week exercise training program on insulin resistance and adiposity in overweight/obese women with PCOS.
Other: Control Group without PCOS
A group of overweight/obese women without PCOS will be enrolled as a control group and will be studied only once at baseline to allow for comparisons between the two study populations.
- Change in Insulin sensitivity as measured by the euglycemic hyperinsulinemic clamp [ Time Frame: Baseline and 16-weeks ]16-weeks of aerobic exercise training on: peripheral insulin sensitivity (euglycemic-hyperinsulinemic clamp) and catecholamines (microdialysis) during a euglycemic-hyperinsulinemic clamp.
- Change in adiposity (whole body measurement by dual x-ray absorptiometry and visceral measured by magnetic resonance imaging) [ Time Frame: Baseline and 16-weeks ]16-weeks of aerobic exercise training on total and free testosterone concentraions and frequency of menstruation, Body lipolysis, and visceral fat.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01150539
|United States, Louisiana|
|Pennington Biomedical Research Center|
|Baton Rouge, Louisiana, United States, 70808|
|Principal Investigator:||Leanne Readman, PhD||Pennington Biomedical Research Center|