Evaluation of Treatments for Homeless Youths
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ClinicalTrials.gov Identifier: NCT01143792 |
Recruitment Status
:
Completed
First Posted
: June 14, 2010
Results First Posted
: April 16, 2013
Last Update Posted
: April 16, 2013
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Substance Abuse | Behavioral: Community Reinforcement Approach (CRA) + HIV prevention Behavioral: Case Management + HIV Prevention Behavioral: Motivational Enhancement Therapy (MET) + HIV prevention | Phase 2 |
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 270 participants |
Allocation: | Randomized |
Intervention Model: | Parallel Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | Evaluation of Treatments for Homeless Youth: CRA, MET and Case Management |
Study Start Date : | September 2006 |
Actual Primary Completion Date : | December 2010 |
Actual Study Completion Date : | June 2012 |

Arm | Intervention/treatment |
---|---|
Experimental: CRA + HIV prevention |
Behavioral: Community Reinforcement Approach (CRA) + HIV prevention
12 sessions of the CRA and 2 sessions of HIV prevention.
|
Active Comparator: Case Management + HIV prevention |
Behavioral: Case Management + HIV Prevention
12 sessions of case management and 2 sessions of HIV prevention.
|
Active Comparator: MET + HIV prevention |
Behavioral: Motivational Enhancement Therapy (MET) + HIV prevention
2 sessions of MET and 2 sessions of HIV prevention.
|
- Substance Use [ Time Frame: Three months ]Percentage of substance use days in prior three months.
- Substance Use [ Time Frame: Six months ]Percentage of substance use days in prior three months
- Substance Use [ Time Frame: Twelve months ]Percentage of substance use days in prior six months
- HIV Risk [ Time Frame: Three months ]Frequency of condoms use in prior three months.
- HIV Risk [ Time Frame: Six months ]Frequency of condoms use in prior three months.
- HIV Risk [ Time Frame: Twelve months ]Frequency of condoms use in prior six months.
- Depressive Symptoms [ Time Frame: Three months ]Beck Depression Inventory - II (BDI-II) total score, range from 0 (no depresion)to 63 (severe depression)
- Depressive Symptoms [ Time Frame: Six months ]Beck Depression Inventory - II (BDI - II) Range from 0 (no depression) to 63 (severe depression)
- Depressive Symptoms [ Time Frame: Twelve months ]Beck Depression Inventory - II (BDI-II) total score, range from 0 (no depression)to 63 (severe depression)

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Ages Eligible for Study: | 14 Years to 20 Years (Child, Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Youth are between the ages of 14-20.
- Youth have plans to remain in the Columbus areas for at least 12 months.
- Youth meets abuse or dependence DSM-IV criteria for Psychoactive Substance Use or Alcohol disorder, as assessed by the computerized diagnostic interview schedule for children (CDISC, Shaffer, 1992).
- Youth agrees to participate in the assessment and treatment intervention.
- Youth meets criteria for homelessness as defined by DHHS.
Exclusion Criteria:
1. Evidence of unremitted psychosis or other condition which would impair their ability to understand and participate in the intervention or consent for research participation (as determined by CDISC).

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01143792
United States, Ohio | |
The Ohio State University | |
Columbus, Ohio, United States, 43210 |
Principal Investigator: | Natasha Slesnick, Ph.D. | Ohio State University |
Responsible Party: | Natasha Slesnick, Ph.D., Ohio State University |
ClinicalTrials.gov Identifier: | NCT01143792 History of Changes |
Other Study ID Numbers: |
2005B0078 R01DA013549 ( U.S. NIH Grant/Contract ) |
First Posted: | June 14, 2010 Key Record Dates |
Results First Posted: | April 16, 2013 |
Last Update Posted: | April 16, 2013 |
Last Verified: | April 2013 |
Keywords provided by Natasha Slesnick, Ohio State University:
Substance abuse Homelessness HIV risk behavior |
Additional relevant MeSH terms:
Substance-Related Disorders Chemically-Induced Disorders Mental Disorders |