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The Evaluation of Therapeutic Efficacy on the Integrated Group Psychotherapy for Patients With Schizophrenia

This study has been completed.
Kaohsiung Medical University
Information provided by (Responsible Party):
National Taiwan University Hospital Identifier:
First received: June 7, 2010
Last updated: December 26, 2012
Last verified: November 2012
Although the patients with schizophrenia can be treated with new generation of antipsychotics medication, additional approaches are necessary to improve schizophrenics' cognitive functions, interpersonal relationships as well as social adjustment. When some of patients return to community, they expose to practical pressure that contribute to worsen and relapse of disease. That further damages patient's cognitive functions. Integrated Psychological Therapy(IPT) on treating schizophrenia has dramatic improvement in recent years; it has formed structured treatment gradually on relieving illusion, hallucination as well as negative symptoms. This study aims at conducting 12-week structured IPT group therapy. The intended subjects are patients, met with DSM-Ⅳ-TR diagnosis of schizophrenia, from community, outpatient and inpatient service. The overall treatments are designed to provide 1-2 hours weekly group therapy which focuses on relieving illusions, hallucination, and negative symptoms. Patients' cognitive functions, ability of emotional adjustment and interpersonal relationship would be evaluated in pre-test and post-test to indicate whether the significant difference exists. There is a controlled group, in which patients who still receive treatment as usual (TAU). The study also compares the evaluation results between IPT group and TAU group, hoping to develop the therapeutic framework for Taiwan people with schizophrenia.

Condition Intervention
Behavioral: Group Psychotherapy

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
Official Title: Department of Psychiatry of NTUH Yun-Lin Branch

Resource links provided by NLM:

Further study details as provided by National Taiwan University Hospital:

Primary Outcome Measures:
  • re-hospitalization rate [ Time Frame: after 3 months of the group psychotherapy ]
    acute symptom relapse and needed to be admitted to the acute ward

Secondary Outcome Measures:
  • Cognitive functions, ability of emotional adjustment, and interpersonal relationship [ Time Frame: 12 months of the group tpsychotherapy ]
    The tests of psychiatric symptoms, cognitive test, anxiety, depression, interpsersonal skill, and emotional adjustment Add Secondary Outcome Measure:The Positive and Negative Syndrome Scale, Beck depression scale, Beck anxiety scale, Beck suicial ideation scale, Cognitive tests (visual spatial test), CPT-IP for attention test

  • The Positive and Negative Syndrome Scale, Beck depression scale, Beck anxiety scale, Beck suicial ideation scale, Cognitive tests (visual spatial test), CPT-IP for attention test [ Time Frame: 12 months of the group psychotherapy ]
    The Positive and Negative Syndrome Scale for psychiatric symptoms, Beck depression scale for depression symptoms, Beck anxiety scale for anxiety symptoms, Beck suicial ideation scale for suicidal ideation evalution Cognitive tests (visual spatial test), CPT-IP for attention test for cognitive function

Enrollment: 50
Study Start Date: May 2010
Study Completion Date: May 2011
Primary Completion Date: May 2011 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
There is no arm in this study.
Behavioral: Group Psychotherapy
integrated group psychotherapy, including the interpersonal and cognitive group therapy


Ages Eligible for Study:   18 Years to 80 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • schizophrenia,
  • can concentrate in group for 30 minutes.

Exclusion Criteria:

  • substance abuse (alcohol, illegal medication),
  • self harm history.
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Please refer to this study by its identifier: NCT01139099

National Taiwan University Hospital Yun-Lin Branch
Yun-lin, Taiwan, 64001
Sponsors and Collaborators
National Taiwan University Hospital
Kaohsiung Medical University
Study Director: Li-Ren Chang, MD Department of Psychiatry in National Taiwan University Hospital Yun-Lin Branch
  More Information

Responsible Party: National Taiwan University Hospital Identifier: NCT01139099     History of Changes
Other Study ID Numbers: 201003068R
Study First Received: June 7, 2010
Last Updated: December 26, 2012

Additional relevant MeSH terms:
Schizophrenia Spectrum and Other Psychotic Disorders
Mental Disorders processed this record on May 25, 2017