DM1 Heart Registry - DM1 Respiratory Registry (DM1-Heart-R)
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|ClinicalTrials.gov Identifier: NCT01136330|
Recruitment Status : Completed
First Posted : June 3, 2010
Last Update Posted : February 20, 2012
Myotonic dystrophy type 1 (DM1) is the most frequent neuromuscular disease in adults. DM1 patients have an impaired prognosis (mean age of death <60 years) due to cardiac and respiratory complications.
Our primary objective was to identify cardiac and respiratory prognostic factors in DM1.
|Condition or disease|
- Patients with genetically proven DM1 who were admitted in Pitié Salpêtrière Hospital from 2000 and 2010 will be identified. These patients systematically underwent neurological, cardiac and respiratory investigations.
- Baseline medical and genetic information will be entered in a dedicated database, including cardiac and respiratory investigations.
- The occurence of severe cardiac and respiratory adverse events will also be collected.
- Statistical analysis will be performed to look for correlations between baseline patient characteristics and cardiac or respiratory adverse events during follow up.
|Study Type :||Observational|
|Actual Enrollment :||914 participants|
|Official Title:||Cardiac and Respiratory Prognostic Factors in Patients With Myotonic Dystrophy Type 1|
|Study Start Date :||May 2010|
|Actual Primary Completion Date :||September 2011|
|Actual Study Completion Date :||September 2011|
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01136330
|Pitié Salpêtrière Hospital|
|Paris, Ile de France, France, 75013|
|Study Director:||Denis Duboc, MD,PhD||APHP|