Artemether-Lumefantrine Effectiveness in Guinea-Bissau 2
|ClinicalTrials.gov Identifier: NCT01133314|
Recruitment Status : Unknown
Verified November 2012 by Bandim Health Project.
Recruitment status was: Active, not recruiting
First Posted : May 28, 2010
Last Update Posted : March 19, 2013
|Condition or disease|
Children from Bissau seeking medical advice and who are recommended treatment for malaria in accordance with the current routines will be included as follows:
All children getting the clinical diagnosis of malaria will be registered and basic information collected.
All children with a positive malaria film and/or a positive RDT will be asked for a capillary blood sample (app. 50 - 100 microliters on a filterpaper). Using PCR the parasitological diagnosis will be verified and if parasites are identified the resistance patterns will be examined. Both the capillary blood samples and the RDTs (if taken by the health staff) will be used in order to examine whether the RDTs can be used for routine monitoring of resistance in an area.
The study does not interfere in the routine treatment of the health staff. None of the children will be followed.
|Study Type :||Observational|
|Estimated Enrollment :||600 participants|
|Official Title:||The Routine Use of Coartem for Treatment of Symptomatic Children With Plasmodium Falciparum in Bissau - 2|
|Study Start Date :||May 2010|
|Actual Primary Completion Date :||December 2012|
|Estimated Study Completion Date :||March 2014|
- Percentage of children treated for malaria with a parasitological confirmed malaria. [ Time Frame: 6 weeks ]The blood samples will be analysed for parasites at the end of the study. The results do not have any impact on the treatment of the children.
- Percentage of the parasites with mutations coding for resistance to antimalarials. [ Time Frame: 2 years ]
Biospecimen Retention: Samples Without DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01133314
|Bandim Health Project|
|Bissau, Bissau Codex, Guinea-Bissau|
|Principal Investigator:||Poul-Erik Kofoed, MD, Ph.d.||Bandim Health Project|