Comment Period Extended to 3/23/2015 for Notice of Proposed Rulemaking (NPRM) for FDAAA 801 and NIH Draft Reporting Policy for NIH-Funded Trials

Immunological Change and the Single Nucleotide Polymorphism (SNP) in Children With Irritable Bowel Syndrome (IBS)

The recruitment status of this study is unknown because the information has not been verified recently.
Verified May 2010 by Chang Gung Memorial Hospital.
Recruitment status was  Recruiting
Information provided by:
Chang Gung Memorial Hospital Identifier:
First received: May 25, 2010
Last updated: May 26, 2010
Last verified: May 2010

Currently, the pathophysiology of Irritable bowel syndrome( IBS) remains unclear . The purpose of this study is want to investigate the immunological changes in the children with IBS.

Irritable Bowel Syndrome

Study Type: Observational
Study Design: Observational Model: Case Control
Time Perspective: Cross-Sectional

Resource links provided by NLM:

Further study details as provided by Chang Gung Memorial Hospital:

Estimated Enrollment: 40
Study Start Date: November 2008
The patient group
healthy control group

Detailed Description:

Irritable bowel syndrome (IBS) is a highly prevalent functional gastrointestinal disorder.Many children suffered from this disease and had impact on their daily life. However, the underlying pathophysiologic mechanisms remain to be elucidate. Dysregulation of the gut immune system is considered an important pathophysiology. We want to investigate the immunological changes in the IBS children.


Ages Eligible for Study:   5 Years to 18 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

out patient clinics in the hospital


Inclusion Criteria:

  • (5-18y/o) with IBS,
  • All patients had chronic or relapsing symptoms of IBS consistent with the ROME II criteria

Exclusion Criteria:

  • A history of psychologic disorders, probiotics, anti-inflammatory, analgesic, or immunosuppressive medication (nonsteroidal anti-inflammatory drugs, steroids) within the past 3 months were excluded
  Contacts and Locations
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Please refer to this study by its identifier: NCT01131442

Chang Gung Memeorial Hospital Recruiting
Keelung, Taiwan
Contact: Man-Chin Hua, M.D.    886-2-24313131 ext 2626   
Principal Investigator: Man-Chin Hua Hua, M.D.         
Sponsors and Collaborators
Chang Gung Memorial Hospital
  More Information

No publications provided by Chang Gung Memorial Hospital

Additional publications automatically indexed to this study by Identifier (NCT Number):
Responsible Party: Chang Gung Memorial Hospital Identifier: NCT01131442     History of Changes
Other Study ID Numbers: CMRPG270371
Study First Received: May 25, 2010
Last Updated: May 26, 2010
Health Authority: Taiwan: Institutional Review Board

Keywords provided by Chang Gung Memorial Hospital:

Additional relevant MeSH terms:
Irritable Bowel Syndrome
Colonic Diseases
Colonic Diseases, Functional
Digestive System Diseases
Gastrointestinal Diseases
Intestinal Diseases
Pathologic Processes processed this record on February 25, 2015