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Effects of Tai Chi on Frailty in Elderly Adults

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ClinicalTrials.gov Identifier: NCT01126723
Recruitment Status : Completed
First Posted : May 20, 2010
Results First Posted : January 30, 2015
Last Update Posted : February 23, 2015
Sponsor:
Collaborators:
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Information provided by (Responsible Party):
Hebrew SeniorLife

Study Description
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Brief Summary:
The aim of this study is determine the effects of Tai Chi exercise, as compared to an education-based control intervention, on cardiovascular and balance system function in older people at risk of developing frailty. We hypothesize that long-term Tai Chi training will improve specific nonlinear properties associated of cardiovascular and balance dynamics in this population.

Condition or disease Intervention/treatment Phase
Frailty Other: Tai Chi Other: Education-Control Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 66 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Treatment
Official Title: The Effects of Tai Chi on the Nonlinear Dynamics of Frailty in Elderly Adults
Study Start Date : September 2010
Actual Primary Completion Date : September 2013
Actual Study Completion Date : September 2013
Arms and Interventions
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Arm Intervention/treatment
Experimental: Tai Chi group Other: Tai Chi
The Tai Chi intervention will consist of a 12 week, instructor-led, group-based Tai Chi training program (two, one-hour sessions per week).
Active Comparator: Educational Control group Other: Education-Control
The Education-Control intervention consists of a 12 week, instructor-led attention control program consisting of health education and mind-body breathing exercises (two, one-hour sessions per week)


Outcome Measures
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Primary Outcome Measures :
  1. Frailty Index [ Time Frame: post-intervention ]
    Frailty is defined as the combination of unintentional weight loss, exhaustion, low physical activity, slow walking speed, and muscular weakness.


Eligibility Criteria
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Information from the National Library of Medicine

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Ages Eligible for Study:   70 Years and older   (Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Men and women over age 70 will be included if they are able to stand and walk unassisted, are free of any acute or unstable medical conditions, and are able to understand directions and participate in the protocol.

Exclusion Criteria:

  • Potential subjects will be excluded 1) if they cannot stand and ambulate unassisted, 2) are experiencing any symptomatic cardiovascular or respiratory disease, or have 3) a myocardial infarction or stroke within 6 months, 4) painful arthritis, spinal stenosis, amputation, painful foot lesions, or neuropathy that limits balance and mobility, 5) systolic BP above 160 or diastolic BP above 100 mm Hg, 6) a cardiac pacemaker, 7) Parkinson's Disease or other neuromuscular disorder, 8) metastatic cancer or immunosuppressive therapy, or 9) have significant visual impairment.
Contacts and Locations
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Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01126723


Locations
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United States, Massachusetts
Hebrew Rehabilitation Center
Roslindale, Massachusetts, United States, 02131
Sponsors and Collaborators
Hebrew SeniorLife
National Institutes of Health (NIH)
National Institute on Aging (NIA)
Investigators
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Principal Investigator: Lewis Lipsitz, MD Hebrew Rehabilitation Center
More Information
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Responsible Party: Hebrew SeniorLife
ClinicalTrials.gov Identifier: NCT01126723    
Other Study ID Numbers: 10-005
R37AG025037 ( U.S. NIH Grant/Contract )
First Posted: May 20, 2010    Key Record Dates
Results First Posted: January 30, 2015
Last Update Posted: February 23, 2015
Last Verified: February 2015
Additional relevant MeSH terms:
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Frailty
Pathologic Processes