Childhood Cancer Survivor Study
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|ClinicalTrials.gov Identifier: NCT01120353|
Recruitment Status : Recruiting
First Posted : May 10, 2010
Last Update Posted : October 6, 2017
|Condition or disease|
The study will focus on the following objectives:
- Characterize survivors' health with respect to disease- and treatment-related factors.
- Investigate the consequences of various intensities of exposure to chemotherapy and/or radiation on health outcomes (e.g., cardiovascular, reproductive, second cancers, etc…).
- Compare the mortality experience of survivors with the general population.
- Characterize the health-related behaviors, patterns of medical care, and medical follow-up needs of survivors.
- Describe patterns of familial aggregation of cancer, including known (and variations of) cancer family syndromes.
- Collect and store biologic samples (saliva, blood, second tumor tissue) to correlate with health outcomes and use for future research.
|Study Type :||Observational|
|Estimated Enrollment :||50000 participants|
|Official Title:||Childhood Cancer Survivor Study|
|Actual Study Start Date :||January 5, 1995|
|Estimated Primary Completion Date :||March 2019|
|Estimated Study Completion Date :||March 2019|
Survivors of cancer, diagnosed under 21 years of age, between 1970 and 1999 This project will study children and young adults exposed to specific therapeutic modalities, including radiation, chemotherapy, and/or surgery, for an increased risk of late-occurring events associated with excess mortality and morbidity.
A group of sibling controls will be identified to provide: (1) the ability to make direct comparisons with the survivors, (2) data on outcomes in a non-cancer population, and (3) additional comparison group to determine consistency of findings between data sources.
- To characterize survivors' health outcomes with respect to disease-, treatment, and genetic-related factors. [ Time Frame: 25 years ]
Biospecimen Retention: Samples With DNA
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01120353
|Contact: Gregory T. Armstrong, MD, MSCEfirstname.lastname@example.org|
Show 31 Study Locations
|Principal Investigator:||Gregory T. Armstrong, MD, MSCE||St. Jude Children's Research Hospital|