Clinical Assessment of Patients With Chronic Obstructive Pulmonary Disease (COPD) and/or Chronic Heart Failure (CHF)
|ClinicalTrials.gov Identifier: NCT01114386|
Recruitment Status : Completed
First Posted : May 3, 2010
Last Update Posted : June 7, 2012
|Condition or disease||Intervention/treatment|
|COPD Heart Failure, Congestive||Procedure: Lung function testing, echocardiography, blood sampling|
|Study Type :||Observational|
|Actual Enrollment :||100 participants|
|Official Title:||Clinical, Functional and Biological Assessment of Patients With Chronic Obstructive Pulmonary Disease (COPD) and/or Chronic Heart Failure(CHF) in Stable Conditions and During Exacerbation|
|Study Start Date :||October 2006|
|Actual Primary Completion Date :||July 2011|
|Actual Study Completion Date :||December 2011|
COPD patients, CHF patients
COPD and CHF patients with smoking history (> 10 pack/years), male and female, older than 50 years, referred to Hospital for dyspnea and chronic cough.
Procedure: Lung function testing, echocardiography, blood sampling
All patients will undergo to:
Blood sampling for routine (haemachrome and differential cells blood count, bilirubin, cholesterol, high density lipoprotein, low density lipoprotein, glycemia, blood urea, blood electrolytes (sodium, potassium, chloride), glutamic-oxaloacetic transaminase, glutamic-pyruvic transaminase, γGT, triglycerides, creatinine, uric acid, creatine phosphokinase, glycosylated haemoglobin).
Blood sampling for selected biomarkers: NTBNP, HS-PCR and IL-6, IL1-β, cellular receptor D6 and TIR8, IL-1 decoy receptor PTX3.
Measurement of arterial blood gases.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01114386
|Azienda Ospedaliero-Universitaria di Modena|
|Modena, Italy, 41124|
|Principal Investigator:||Leonardo M Fabbri, MD||University of Modena and Reggio Emilia|