COVID-19 is an emerging, rapidly evolving situation.
Get the latest public health information from CDC:

Get the latest research information from NIH: Menu

Iyengar Yoga for Young People With Irritable Bowel Syndrome

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT01107977
Recruitment Status : Completed
First Posted : April 21, 2010
Last Update Posted : November 28, 2016
Information provided by (Responsible Party):
University of California, Los Angeles

Brief Summary:
Irritable bowel syndrome (IBS) affects as many as 14% of high school-aged students. Symptoms include discomfort in the abdomen, along with diarrhea and/or constipation and other gastroenterological symptoms, which can significantly impact quality of life and daily functioning of patients. Emotional stress appears to exacerbate IBS symptoms suggesting that mind-body interventions reducing arousal may prove beneficial. Often symptoms can be traced to childhood and adolescence, making the early manifestation of IBS important to understand. The current study focuses on young people aged 14-26 years of age with IBS. The study will test the potential benefits of Iyengar yoga (IY) on clinical symptoms, psychospiritual functioning and visceral sensitivity. Yoga is thought to bring physical, psychological and spiritual benefits to practitioners and has been associated with reduced stress and pain. Through its focus on restoration and use of props, IY is especially designed to decrease arousal and promote psychospiritual resources in physically compromised individuals. Sixty-four IBS patients aged 14-26 will be randomly assigned to a standardized 6-week biweekly IY group-based program (1.5 hour sessions) or a wait-list usual care control group. The groups will be compared on the primary clinical outcomes of IBS symptoms, quality of life and global improvement at post-treatment and 2 month follow-up. Secondary outcomes will include visceral pain sensitivity assessed with a standardized laboratory task (water load task), and psychospiritual variables including coping, self-efficacy, mood, acceptance and mindfulness. It is hypothesized that IY will be safe and feasible: with less than 20% attrition; and the IY group will demonstrate significantly improved outcomes compared to controls, with physiological and psychospiritual mechanisms contributing to improvements; clinical treatment gains will be maintained at 2 months following yoga.

Condition or disease Intervention/treatment Phase
Irritable Bowel Syndrome Behavioral: Iyengar yoga Not Applicable

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 58 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Outcomes Assessor)
Primary Purpose: Treatment
Official Title: Iyengar Yoga for Young People With Irritable Bowel Syndrome
Study Start Date : January 2010
Actual Primary Completion Date : December 2013
Actual Study Completion Date : December 2013

Arm Intervention/treatment
Experimental: Iyengar yoga Behavioral: Iyengar yoga
Iyengar yoga twice/week for 6 weeks

No Intervention: Waitlist control

Primary Outcome Measures :
  1. Irritable bowel symptoms [ Time Frame: baseline (within 2 weeks of receiving intervention) ]
  2. Irritable bowel symptoms [ Time Frame: post-intervention (within 2 weeks of completing intervention) ]
  3. Irritable bowel symptoms [ Time Frame: follow up (2 months after completion of intervention) ]
  4. Quality of Life [ Time Frame: baseline (within 2 weeks of receiving intervention) ]
  5. Quality of Life [ Time Frame: post-intervention (within 2 weeks of completing intervention) ]
  6. Quality of Life [ Time Frame: follow up (2 months after completion of intervention) ]

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

Layout table for eligibility information
Ages Eligible for Study:   14 Years to 26 Years   (Child, Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No

Inclusion Criteria:

  • Male and female youth will be eligible for the study if they meet the following criteria:

    • Age 14-26 years.
    • Diagnosis of IBS, using ROME III pediatric criteria for patients aged 14-17 years, and ROME III adult criteria for 18-26 year-olds.
    • Able and willing to give written informed assent or consent and comply with the requirements of the study protocol.
    • Ability to speak and understand English.

Exclusion Criteria:

  • Any other injury, disease, metabolic dysfunction, physical examination finding, or clinical laboratory finding giving reasonable suspicion that it might affect the interpretation of the results or render the patient at high risk from treatment complications.

    • Inability to comply with study and follow-up procedures.
    • Currently pregnant.
    • Previous practice of yoga within the past three months.
    • Inability to speak and understand English.
    • Plan to begin a new treatment within 2 weeks of the IYP.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT01107977

Layout table for location information
United States, California
UCLA Pediatric Pain Program
Los Angeles, California, United States, 90064
Sponsors and Collaborators
University of California, Los Angeles
Layout table for investigator information
Principal Investigator: Subhadra Evans, Ph.D. University of California, Los Angeles
Publications of Results:
Publications automatically indexed to this study by Identifier (NCT Number):
Layout table for additonal information
Responsible Party: University of California, Los Angeles Identifier: NCT01107977    
Other Study ID Numbers: 1K01AT005093 ( U.S. NIH Grant/Contract )
First Posted: April 21, 2010    Key Record Dates
Last Update Posted: November 28, 2016
Last Verified: November 2016
Additional relevant MeSH terms:
Layout table for MeSH terms
Irritable Bowel Syndrome
Pathologic Processes
Colonic Diseases, Functional
Colonic Diseases
Intestinal Diseases
Gastrointestinal Diseases
Digestive System Diseases