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2D and Tissue Doppler Imaging Echocardiography Analysis of Left Ventricular Regional Wall Motion and Prognosis (TDI)

The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified June 2011 by Chang Gung Memorial Hospital.
Recruitment status was:  Recruiting
Information provided by (Responsible Party):
Chang Gung Memorial Hospital Identifier:
First received: March 23, 2010
Last updated: July 28, 2014
Last verified: June 2011

Development of myocardial ischemia, and/or myocarditis would induce different changes in myocardial contraction behavior pattern,which maybe very subtle, and may not be detected by the 2D and m-mode echocardiography examinations. According to tissue Doppler imaging(TDI), they can be depicted by different models of echo with higher frame rates. In addition, many studies using TDI have significantly contributed of efforts to evaluate systolic and diastolic function and prognosis.

This study assess the value of the indices of left ventricular function obtained by using TDI in patient with coronary artery disease(CAD). We hypothesized that TDI will add incremental value for regional wall motion abnormality of CAD and its prognosis.

Coronary Artery Disease

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Prospective

Resource links provided by NLM:

Further study details as provided by Chang Gung Memorial Hospital:

Primary Outcome Measures:
  • all cause mortality [ Time Frame: one year ]

Estimated Enrollment: 500
Study Start Date: February 2008
Estimated Study Completion Date: December 2015
Estimated Primary Completion Date: December 2015 (Final data collection date for primary outcome measure)
one,two,and three vessels disease; mortality


Ages Eligible for Study:   20 Years to 90 Years   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
Accoring to recommendation of ACC/AHA, patient had classI indication to perform coronary angiography

Inclusion Criteria:

  1. Angina
  2. Acue coronary syndrome
  3. Left ventricular systolic dysfunction

Exclusion Criteria:

  1. Significant valvular disease
  2. Active cancer status
  3. Acute Renal failure
  4. Contrast allergy history
  5. Pregnancy
  Contacts and Locations
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Please refer to this study by its identifier: NCT01092429

Contact: Fun-Chung Lin, MD

Cheng Gung Memorial Hospital at Linkou Recruiting
Taipei, Taiwan
Contact: Tsang-Tang Hsieh, MD    +886 -3-3196200 ext 3656   
Sponsors and Collaborators
Chang Gung Memorial Hospital
  More Information

Responsible Party: Chang Gung Memorial Hospital Identifier: NCT01092429     History of Changes
Other Study ID Numbers: 96-1504B
Study First Received: March 23, 2010
Last Updated: July 28, 2014

Keywords provided by Chang Gung Memorial Hospital:

Additional relevant MeSH terms:
Coronary Artery Disease
Myocardial Ischemia
Coronary Disease
Heart Diseases
Cardiovascular Diseases
Arterial Occlusive Diseases
Vascular Diseases processed this record on September 18, 2017