The Cyclocapnic Method for Measurement of Chemosensitivity
|ClinicalTrials.gov Identifier: NCT01049256|
Recruitment Status : Unknown
Verified January 2010 by Imperial College London.
Recruitment status was: Recruiting
First Posted : January 14, 2010
Last Update Posted : January 14, 2010
We aim to test our method for measuring chemosensitivity (the ventilatory response to a change in carbon dioxide), which uses sinusoidal carbon dioxide stimuli.
- Carbon dioxide sensitivity is dependent on the cycle time over which we administer the gas (frequency).
- Chemoreflex gain decreases as deadspace increases.
|Condition or disease||Intervention/treatment||Phase|
|Periodic Breathing Heart Failure||Other: carbon dioxide||Phase 1|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||45 participants|
|Intervention Model:||Single Group Assignment|
|Masking:||None (Open Label)|
|Primary Purpose:||Basic Science|
|Official Title:||Developing an Improved Measure of Chemosensitivity for the Study of Periodic Breathing in Heart Failure: the Cyclocapnic Method|
|Study Start Date :||January 2008|
|Estimated Primary Completion Date :||April 2010|
|Estimated Study Completion Date :||October 2010|
Other: carbon dioxide
- Chemoreflex gain as measured by cyclocapnic method [ Time Frame: every minute ]
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01049256
|Contact: Darrel P Francis, MD||+44 207 594 firstname.lastname@example.org|
|St Mary's Hospital||Recruiting|
|London, United Kingdom, W2 1LA|
|Contact: Resham Baruah, MB BS 020 75941027 email@example.com|
|Contact: Darrel P Francis, MD +44 207 594 1093 firstname.lastname@example.org|
|Principal Investigator:||Darrel P Francis, MD||Imperial College London|