Virus Shedding and Environmental Deposition of a Novel Influenza Virus
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|ClinicalTrials.gov Identifier: NCT01046734|
Recruitment Status : Completed
First Posted : January 12, 2010
Last Update Posted : September 27, 2012
An influenza pandemic has recently been declared, involving the novel A(H1N1) 'swine flu' virus. This has spread to almost 100 countries worldwide in less than two months, causing widespread disease so far in Mexico, USA and Canada. It is highly likely that over the next 12 months, many countries including the UK will be affected by widespread illness. In the UK this wave of intense flu activity is most likely to occur in late autumn 2009.
Very little is known about the new H1N1 pandemic virus. For example we do not know how long the virus is excreted by infected humans and how much virus is spread to surfaces and carried in the air. This is very important to know as soon as possible because it affects the advice that will be given to healthcare workers about controlling the spread of infection to themselves and other patients. Similarly we need this information so we can give good quality advice to families who will have to look after each other in their own homes.
The best way to obtain this information is to ask patients who get pandemic flu soon (in August, September and October) to help us by agreeing to give a daily nose swab sample for just over one week so we can see how much virus is in the nose day by day and how quickly this disappears. At the same time we will take samples from hard surfaces in a patient's room or home and sample the air using a special filter device. We can then work out how much virus is being excreted, how long the 'danger period' is, whether surfaces are more or less important than the air that we breathe (in terms of catching the virus) and if we can advise on a 'safe distance' from the patient, beyond which there is relatively little chance of catching the illness.
|Condition or disease|
|Novel (H1N1) Influenza|
|Study Type :||Observational|
|Actual Enrollment :||105 participants|
|Official Title:||Virus Shedding and Environmental Deposition of Novel A(H1N1) Pandemic Influenza Virus|
|Study Start Date :||September 2009|
|Actual Primary Completion Date :||March 2011|
|Actual Study Completion Date :||March 2011|
- Virus shedding and deposition as measured by virus culture and quantitative polymerase chain reaction (PCR). [ Time Frame: 6 months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01046734
|Leicester University Hospitals NHS Trust|
|Leicester, United Kingdom|
|Nottingham University Hospitals NHS Trust|
|Nottingham, United Kingdom, NG5 1PB|
|Sheffield Teaching Hospitals NHS Trust|
|Sheffield, United Kingdom|
|Principal Investigator:||Jonathan Van-Tam, MD||University of Nottingham|