Salivary Flow Rate and Oral Function (SOF)
The purpose of this study was to investigate if salivary flow rate is important to maintain adequate oral functions.
|Study Design:||Time Perspective: Cross-Sectional|
|Official Title:||Effect of Hyposalivation on Mastication and Speech|
|Study Start Date:||August 2006|
|Study Completion Date:||November 2007|
|Primary Completion Date:||August 2006 (Final data collection date for primary outcome measure)|
Subjects with normal salivary flow rate
Subjects presenting low salivary flow rate as a side effect of systemic isotretinoin therapy.
Hyposalivation may damage oral functions. Therefore, the aim of this study was to evaluate whether patients under hyposalivation present damaged mastication and speech. Forty subjects composed 2 groups: Control (C) and hyposalivation (H). Masticatory performance (MP) was carried out using artificial material and a 10-sieve method. Mandibular movements during speech were obtained using a 3D jaw-tracking device. Neither mastication nor speech have been impaired by low salivary flow rate.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01020084
|Piracicaba Dental School|
|Piracicaba, São Paulo, Brazil, 13414-903|
|Study Chair:||Renata CM Rodrigues Garcia, PhD||Piracicaba Dental School|
|Study Director:||Alrair A Del Bel Cury, PhD||Piracicaba Dental School|
|Principal Investigator:||Simone G Farias Gomes, MS||Piracicaba Dental School|