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Cardiovascular Risk Evaluation and Antiretrovirals in HIV (CREATE1)

This study has been completed.
Guy's and St Thomas' NHS Foundation Trust
Information provided by:
King's College London Identifier:
First received: November 16, 2009
Last updated: NA
Last verified: November 2009
History: No changes posted
The purpose of the study is to determine the main factors contributing to predicted 10 year cardiovascular risk in an HIV infected cohort, and the role of anti-HIV drug use in altering this risk

Cardiovascular Risk HIV Infections

Study Type: Observational
Study Design: Observational Model: Cohort
Time Perspective: Cross-Sectional
Official Title: Predicted 10-year Coronary Heart Disease Risk in HIV and Implications for Clinical Management: the CREATE Study

Resource links provided by NLM:

Further study details as provided by King's College London:

Primary Outcome Measures:
  • 10 year predicted cardiovascular risk [ Time Frame: AT time of clinic attendence ]

Secondary Outcome Measures:
  • coronary heart disease risk [ Time Frame: at time of clinic attendence ]

Enrollment: 1024
Study Start Date: June 2005
Study Completion Date: November 2006
Primary Completion Date: September 2006 (Final data collection date for primary outcome measure)
unselected HIV outpatient attendees
All HIV patients attending for general HIV care at 2 London Hospitals


Ages Eligible for Study:   18 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
All HIV outpatients patients attending two London Hospitals

Inclusion Criteria:

  • Serologically proven HIV infection
  • Attending general HIV outpatient clinic

Exclusion Criteria:

  • Attending a specialist outpatient clinic which might lead to recruitment bias
  Contacts and Locations
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Please refer to this study by its identifier: NCT01015092

United Kingdom
Guys & ST Thomas' Foundation Hospitals
London, United Kingdom, SE30AA
Sponsors and Collaborators
King's College London
Guy's and St Thomas' NHS Foundation Trust
Principal Investigator: Barry S Peters, MB BS. MD King's College London
  More Information

Responsible Party: Dr Barry Stephen Peters, Kings College London Identifier: NCT01015092     History of Changes
Other Study ID Numbers: 05/Q0702/156
Study First Received: November 16, 2009
Last Updated: November 16, 2009

Keywords provided by King's College London:
Coronary hear disease

Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases processed this record on September 21, 2017