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Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana

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ClinicalTrials.gov Identifier: NCT01001741
Recruitment Status : Completed
First Posted : October 27, 2009
Last Update Posted : September 17, 2015
Sponsor:
Information provided by (Responsible Party):
University of Pennsylvania

Study Description
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Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information
Brief Summary:
While medication adherence is critical to successful treatment of HIV, there are few studies of interventions demonstrating improvements in adherence. This may be a particular challenge in the developing world, which has a larger burden of HIV but fewer resources than industrialized countries. The investigators propose a randomized controlled trial of cellular phone text message reminders to improve medication adherence. Our pilot study will be set in a large HIV clinic in Gaborone, Botswana, where Penn researchers have collaborated on research projects in the past. The primary study outcome will be antiretroviral medication adherence.

Condition or disease Intervention/treatment Phase
HIV Infections Other: Cell phone text message Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 128 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: None (Open Label)
Primary Purpose: Supportive Care
Official Title: A Pilot Study of Cellular Phone Text Message Reminders to Improve HIV Medication Adherence at Independence Surgery Clinic Gaborone, Botswana
Study Start Date : June 2008
Actual Primary Completion Date : August 2009
Actual Study Completion Date : August 2009

Resource links provided by the National Library of Medicine

MedlinePlus related topics: HIV/AIDS
U.S. FDA Resources

Arms and Interventions
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Intervention Details:
    Other: Cell phone text message
    We will use cellular text messages to remind patients of impending drug prescription refills and scheduled visits to their healthcare provider.

Outcome Measures
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Primary Outcome Measures :
  1. HIV medication adherence [ Time Frame: Monthly ]

Eligibility Criteria
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Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

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Ages Eligible for Study:   21 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • HIV infected
  • 21 years of age or older

Exclusion Criteria:

  • Subjects who do not intend to have continuous follow-up care and monthly medication refills at Independence Surgery for at least the next six months
Contacts and Locations
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Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01001741


Locations
Botswana
Independence Surgery
Gaborone, Botswana
Sponsors and Collaborators
University of Pennsylvania
Investigators
Study Director: Darren Linkin, MD University of Pennsylvania
Principal Investigator: Harvey Friedman, MD University of Pennsylvania
Study Director: James Thompson, MBA Wharton Business School, UPenn
Study Director: Andrew Steenhoff University of Pennsylvania
More Information
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Study Description Study Design Arms and Interventions Outcome Measures Eligibility Criteria Contacts and Locations More Information

Publications of Results:

Responsible Party: University of Pennsylvania
ClinicalTrials.gov Identifier: NCT01001741     History of Changes
Other Study ID Numbers: 805891
NIH: P30 AI 045008
First Posted: October 27, 2009    Key Record Dates
Last Update Posted: September 17, 2015
Last Verified: June 2010

Keywords provided by University of Pennsylvania:
HIV
Antiretrovirals
Adherence
 Text messaging
Antiretroviral adherence
Treatment experienced

Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
 Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases