Pilot Study of Text Message Reminders to Improve HIV Medication Adherence in Botswana

This study has been completed.

Sponsor:

Information provided by (Responsible Party):

University of Pennsylvania

ClinicalTrials.gov Identifier:

NCT01001741

First received: October 23, 2009

Last updated: September 16, 2015

Last verified: June 2010

History of Changes

Purpose

While medication adherence is critical to successful treatment of HIV, there are few studies of interventions demonstrating improvements in adherence. This may be a particular challenge in the developing world, which has a larger burden of HIV but fewer resources than industrialized countries. The investigators propose a randomized controlled trial of cellular phone text message reminders to improve medication adherence. Our pilot study will be set in a large HIV clinic in Gaborone, Botswana, where Penn researchers have collaborated on research projects in the past. The primary study outcome will be antiretroviral medication adherence.

Condition	Intervention
HIV Infections	Other: Cell phone text message


Study Type:	Interventional
Study Design:	Allocation: Randomized Intervention Model: Parallel Assignment Masking: Open Label Primary Purpose: Supportive Care
Official Title:	A Pilot Study of Cellular Phone Text Message Reminders to Improve HIV Medication Adherence at Independence Surgery Clinic Gaborone, Botswana

Resource links provided by NLM:

MedlinePlus related topics: HIV/AIDS

U.S. FDA Resources

Further study details as provided by University of Pennsylvania:

Primary Outcome Measures:

HIV medication adherence [ Time Frame: Monthly ] [ Designated as safety issue: No ]


Enrollment:	128
Study Start Date:	June 2008
Study Completion Date:	August 2009
Primary Completion Date:	August 2009 (Final data collection date for primary outcome measure)

Intervention Details:

We will use cellular text messages to remind patients of impending drug prescription refills and scheduled visits to their healthcare provider.

Eligibility


Ages Eligible for Study:	21 Years and older (Adult, Senior)
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

HIV infected
21 years of age or older

Exclusion Criteria:

Subjects who do not intend to have continuous follow-up care and monthly medication refills at Independence Surgery for at least the next six months

Contacts and Locations

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.

Please refer to this study by its ClinicalTrials.gov identifier: NCT01001741

Locations


Botswana
Independence Surgery
Gaborone, Botswana

Sponsors and Collaborators

University of Pennsylvania

Investigators


Study Director:	Darren Linkin, MD	University of Pennsylvania
Principal Investigator:	Harvey Friedman, MD	University of Pennsylvania
Study Director:	James Thompson, MBA	Wharton Business School, UPenn
Study Director:	Andrew Steenhoff	University of Pennsylvania

More Information

Publications:

Reid MJ, Dhar SI, Cary M, Liang P, Thompson J, Gabaitiri L, Steele K, Mayisela S, Dickinson D, Friedman H, Linkin DR, Steenhoff AP. Opinions and attitudes of participants in a randomized controlled trial examining the efficacy of SMS reminders to enhance antiretroviral adherence: a cross-sectional survey. J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):e86-8. doi: 10.1097/QAI.0b013e3182a9c72b.


Responsible Party:	University of Pennsylvania
ClinicalTrials.gov Identifier:	NCT01001741 History of Changes
Other Study ID Numbers:	805891 NIH: P30 AI 045008
Study First Received:	October 23, 2009
Last Updated:	September 16, 2015
Health Authority:	United States: Institutional Review Board Botswana: Ministry of Health

Keywords provided by University of Pennsylvania:


HIV Antiretrovirals Adherence	Text messaging Antiretroviral adherence Treatment experienced

Additional relevant MeSH terms:


HIV Infections Lentivirus Infections Retroviridae Infections RNA Virus Infections Virus Diseases	Sexually Transmitted Diseases, Viral Sexually Transmitted Diseases Immunologic Deficiency Syndromes Immune System Diseases

ClinicalTrials.gov processed this record on September 30, 2016

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