Effect of Aerobic Training on Asthmatic Patients
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ClinicalTrials.gov Identifier: NCT00989365 |
Recruitment Status :
Completed
First Posted : October 5, 2009
Last Update Posted : October 5, 2009
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Anxiety Depression Airway Inflammation | Other: Aerobic training | Not Applicable |
One-hundred patients with moderate or severe persistent asthma, age ranging from 20 to 50 years-old recruited after a medical consultation. Asthma diagnosis based on GINA1 and patients were under medical treatment for at least 6-months and considered clinically stable (no crises and changes in medication for at least 30 days). Patients diagnosed with cardiovascular, pulmonary or musculoskeletal diseases impairing exercise training were excluded.
Experimental Design: Patients were studied between 2 medical consultation to avoid changes in medication during the study and patients were randomized (by drawing lots) into either Control or Training groups. CG was submitted to a 4-hour educational program and a breathing exercise program and TG was submitted to the same CG procedures plus an aerobic training program individually based on VO2max. Before and after the intervention, patients performed pulmonary function test and cardiopulmonary exercise testing and as well as fulfilled questionnaires to quantify asthma specific HRQL and anxiety and depression levels. Asthma daily symptoms were evaluated monthly.
Study Type : | Interventional (Clinical Trial) |
Actual Enrollment : | 100 participants |
Allocation: | Randomized |
Intervention Model: | Single Group Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | Effect of Aerobic Training on Psychosocial Morbidity, Symptoms, Airway Inflammation and Autonomic Modulation in Asthmatic Patients |
Study Start Date : | January 2007 |
Actual Primary Completion Date : | September 2009 |
Actual Study Completion Date : | September 2009 |

Arm | Intervention/treatment |
---|---|
Patient cousenling
Improve medicine use Self control asthma crisis Ambient hygiene
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Other: Aerobic training
Treadmill training
Other Name: Exercise conditioning |
- psychosocial morbidity and airway inflammation [ Time Frame: 3 months ]
- autonomic modulation, aerobic capacity, pulmonary function [ Time Frame: 3 months ]

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Ages Eligible for Study: | 20 Years to 50 Years (Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- 20-50 years old
- moderate and severe asthma
Exclusion Criteria:
- other pulmonary or cardiovascular disease

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00989365
Brazil | |
Clinical Hospital, School of Medicine, University of São Paulo | |
São Paulo, Brazil, 05403-000 |
Study Chair: | Celso RF Carvalho, PhD | School of Medicine, University of São Paulo |
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Celso Ricardo Fernandes de Carvalho, School of Medicine, University of São Paulo |
ClinicalTrials.gov Identifier: | NCT00989365 |
Other Study ID Numbers: |
Asthmatraining |
First Posted: | October 5, 2009 Key Record Dates |
Last Update Posted: | October 5, 2009 |
Last Verified: | October 2009 |
Aerobic Exercise Exercise |
Inflammation Pathologic Processes |