TRANSCRIBE (Transcriptomic Analysis of Left Ventricular Gene Expression)
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ClinicalTrials.gov Identifier: NCT00985049 |
Recruitment Status :
Recruiting
First Posted : September 28, 2009
Last Update Posted : May 11, 2021
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Condition or disease |
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Cardiovascular Diseases |
Study Type : | Observational |
Estimated Enrollment : | 350 participants |
Observational Model: | Cohort |
Time Perspective: | Prospective |
Official Title: | Whole Genome Expression of Left Ventricular Myocardium During Cardiac Surgery |
Study Start Date : | March 2009 |
Estimated Primary Completion Date : | December 2024 |
Estimated Study Completion Date : | December 2024 |

- Differential gene expression [ Time Frame: Immediate ]
Biospecimen Retention: Samples With DNA

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Ages Eligible for Study: | 20 Years and older (Adult, Older Adult) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Sampling Method: | Non-Probability Sample |
Inclusion Criteria:
- Aged greater than 20 years
- Undergoing aortic valve surgery with or without CABG surgery
- Receive and apical vent as part of the surgery
Exclusion Criteria:
- Will not receive an apical left ventricular vent

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT00985049
Contact: Jochen D Muehlschlegel, MD, MMSc | 617-732-7330 | jmuehlschlegel@partners.org |
United States, Massachusetts | |
Brigham and Women's Hospital | Recruiting |
Boston, Massachusetts, United States, 02115 | |
Principal Investigator: Jochen D Muehlschlegel, MD |
Principal Investigator: | Jochen D. Muehlschlegel, MD | Brigham and Women's Hospital |
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Responsible Party: | Jochen Daniel Muehlschlegel, MD, Associate Professor of Anesthesia, Brigham and Women's Hospital |
ClinicalTrials.gov Identifier: | NCT00985049 |
Other Study ID Numbers: |
2007p002323 R01HL118266 ( U.S. NIH Grant/Contract ) |
First Posted: | September 28, 2009 Key Record Dates |
Last Update Posted: | May 11, 2021 |
Last Verified: | May 2021 |
Cardiovascular Diseases |