Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects
Patients suffering from Thalassemia or another hemoglobinopathies required regular blood transfusions. The complications and adverse effects of blood transfusions can be classified as immediate and late. Among the immediate effects the most common are allergic reactions and fever, besides congestive heart failure in patients with cardiomyopathy. The late effects are mostly related to blood transmitted infections like HIV or Hepatitis C infections.
The purpose of this study is to summarize the data of those complications in a cohort of 100 patients receiving regular blood transfusion.
|Study Design:||Observational Model: Case-Only
Time Perspective: Retrospective
|Official Title:||Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects.|
|Study Start Date:||May 2009|
|Study Completion Date:||November 2010|
|Primary Completion Date:||November 2010 (Final data collection date for primary outcome measure)|
Patients receiving blood transfusions
All the patients with blood disorders that require blood transfusions
Other: Clinical medical record summary
Summary of immediate and late adverse effects of blood transfusions
About 100 patients aged several months to 50 years are treated in the Pediatric Hematology Unit, most of those patients receive blood transfusions monthly. The adverse reactions were routinely recorded during each transfusion. All the patients were also screened annually for the incidence of blood transmitted infections principally HIV and Hepatitis C. All those records will be systematically screened and all the immediate or late adverse reactions and complications related to blood transfusions will be summarized.
A second goal of this study will be to control the staff strictness related to the ministry of health protocol dealing to blood transfusions.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00971880
|Pediatric Hematology Unit and Pediatric Dpt B - HaEmek Medical Center|
|Afula, Israel, 18101|